Combodart
Combodart is used in men to treat an enlarged prostate (benign prostatic hyperplasia) - a non-cancerous growth of the prostate caused by overproduction of a hormone called dihydrotestosterone, in patients already controlled with dutasteride and tamsulosin administered to the time. Combodart is a combination of two different medicines called dutasteride and tamsulosin. Dutasteride belongs to the group of medicines called 5-alpha reductase enzyme inhibitors and tamsulosin belongs to the group of medicines called alpha-blockers. As the prostate enlarges, it can lead to urinary problems such as difficulty in the flow of urine and a need to urinate more frequently. It can also cause the urine stream to be less and less strong.
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Select your preferred options and see the best price
| Pack | Price (£) | ||
|---|---|---|---|
| Combodart | 0.5/0.4mg | 30 Capsules | 43.00 |
| Combodart | 0.5/0.4mg | 60 Capsules | 79.00 |
| Combodart | 0.5/0.4mg | 90 Capsules | 114.00 |
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Combodart Capsules for Prostate Enlargement and Urinary Support
Combodart is a medicine used to treat men with an enlarged prostate (benign prostatic hyperplasia, BPH). It combines two active ingredients, one that shrinks the prostate over time and another that relaxes the muscles in the prostate and bladder neck to improve urine flow. This dual action makes Combodart a strong choice for reducing urinary problems associated with prostate enlargement, such as weak stream, frequent urination, and difficulty starting or stopping.
If you want an effective BPH treatment that supports better urinary flow and reduces prostate-related urinary symptoms, Combodart capsules are a reliable option. You can order Combodart capsules online from Pharmacy Planet after a short and free consultation reviewed by one of our UK prescribers.
What Are Combodart Capsules?
Combodart capsules are a combination medicine containing two drugs: a 5-alpha-reductase inhibitor (that reduces prostate size over time) and an alpha-blocker (that relaxes prostate and bladder neck muscles). This combination is used when an enlarged prostate (BPH) leads to consistent urinary symptoms and when single-drug therapy may not be enough. Because the prostate wraps around the urethra, enlargement can press on the urethra and narrow the urine passage. Combodart works both to reduce that pressure (by shrinking the prostate) and to relax muscle tone (to improve flow).
Combodart capsules are commonly prescribed to manage symptoms including frequent need to urinate, weak or slow urine flow, difficulty starting or stopping urination, urgency or frequent night-time urination, and reducing risk of urinary retention or surgery due to prostate enlargement.
How Do Combodart Capsules Work?
Combodart works via two complementary mechanisms. For prostate shrinkage, one active component blocks the enzyme that converts testosterone into dihydrotestosterone (DHT), the hormone responsible for prostate growth. Lower DHT leads to gradual shrinking of the prostate gland. For muscle relaxation, the other active ingredient relaxes smooth muscles in the prostate and bladder neck. This reduces resistance around the urethra and allows urine to flow more easily.
Together, these effects relieve obstruction, improve urine flow, reduce urinary frequency and lower the risk of acute urinary retention or the need for prostate surgery.
How to Use Combodart Capsules?
Take Combodart exactly as directed by your prescriber. Swallow one capsule daily about 30 minutes after the same meal each day. Swallow the capsule whole with water, and do not chew or open it, as the contents can irritate your mouth or throat.
Useful Tips for Best Results:
- Take Combodart at the same time each day.
- Swallow the capsule whole with a full glass of water.
- Take it 30 minutes after a meal to help absorption.
- Do not skip doses, as long-term use is often needed for full benefits.
- If you miss a dose, skip it and take the next dose at the usual time. Do not double the dose.
Who Can Use Combodart Capsules?
Combodart is generally suitable for men diagnosed with moderate to severe benign prostatic hyperplasia (BPH). It may help those experiencing urinary symptoms such as weak flow, frequent urination or sudden urgency, and can be an option for men at risk of urinary retention or needing long-term prostate management.
Combodart is not appropriate for women, children or anyone under 18. It is also unsuitable for individuals allergic to dutasteride, tamsulosin or any of the capsule ingredients. Men with severe liver disease or a history of low blood pressure causing dizziness or fainting should avoid it as tamsulosin can further lower blood pressure.
Possible Side Effects of Combodart Capsules
Like all medicines, Combodart can cause side effects, but not everyone gets them.
Common Side Effects (may affect >1 in 10 men):
- Impotence (difficulty getting or keeping an erection)
- Decreased sexual drive (libido)
- Difficulty with ejaculation or decreased semen volume
- Breast enlargement or tenderness (gynaecomastia)
- Dizziness, especially when standing up quickly
Uncommon Side Effects (may affect ≤1 in 100):
- Drop in blood pressure on standing, palpitations or irregular heartbeat, digestive issues (nausea, diarrhoea, constipation, stomach discomfort), weakness or tiredness, nasal congestion or runny/blocked nose
Rare But Serious Side Effects — Seek Medical Help Immediately:
- Swelling of face, lips, tongue, throat or limbs (angioedema)
- Severe dizziness or fainting
- Persistent or painful erection (priapism)
- Serious skin reactions (rash, blisters, peeling skin)
Can Combodart Interact with Other Medicines?
Combodart can interact with some medicines. Tell your prescriber about everything you are taking before starting treatment. Extra care is needed with medicines that lower blood pressure (including other alpha-blockers), strong liver enzyme inhibitors (some antifungals/antibiotics), and medicines for erectile dysfunction (can increase light-headedness). Also mention any long-term heart medicines, treatments affecting liver function, and any new medicines started during treatment.
Consultation and Prescription Process at Pharmacy Planet
Here's how you can request and receive your treatment at Pharmacy Planet:
- Complete the online consultation and share details about your urinary symptoms, prostate history and general health.
- One of our UK prescribers reviews your answers to decide whether Combodart is suitable for you.
- If approved, your Combodart capsules will be delivered discreetly to your door.
Combodart combines two active ingredients for treating enlarged prostate (BPH): one shrinks the prostate over time and another relaxes muscles in the prostate and bladder neck to improve urine flow. This dual action reduces urinary problems including weak stream, frequent urination, and difficulty starting or stopping.
A combination of a 5-alpha-reductase inhibitor (reduces prostate size) and an alpha-blocker (relaxes prostate/bladder neck muscles). Used when BPH causes consistent urinary symptoms and single-drug therapy is insufficient. Prescribed for frequent urination, weak flow, difficulty starting/stopping, urgency, night-time urination, and reducing risk of urinary retention.
Prostate shrinkage: Blocks the enzyme converting testosterone to DHT, gradually shrinking the prostate. Muscle relaxation: Relaxes smooth muscles in the prostate and bladder neck, reducing urethral resistance. Together these relieve obstruction, improve flow, reduce frequency, and lower the risk of urinary retention or prostate surgery.
One capsule daily, 30 minutes after the same meal each day. Swallow whole with water — do not chew or open. Do not skip doses. If a dose is missed, skip it and take the next at the usual time — never double dose.
Suitable for men with moderate to severe BPH symptoms, weak flow, frequent urination, urgency, or risk of urinary retention.
Not suitable for women, children/under 18, those allergic to dutasteride/tamsulosin, men with severe liver disease, or history of low blood pressure causing dizziness/fainting.
Common: Impotence, decreased libido, ejaculation difficulty/reduced semen volume, breast enlargement/tenderness, dizziness when standing
Uncommon: Blood pressure drop on standing, palpitations, digestive issues, weakness/tiredness, nasal congestion
Serious (seek immediate help): Angioedema, severe dizziness/fainting, priapism, serious skin reactions
Extra care needed with blood pressure medicines/alpha-blockers, strong liver enzyme inhibitors (antifungals/antibiotics), and erectile dysfunction medicines. Mention long-term heart medicines, liver treatments, and any new medicines started during treatment to your prescriber.
Here's how you can request and receive your treatment at Pharmacy Planet:
- Complete the online consultation and share details about your urinary symptoms, prostate history and general health.
- One of our UK prescribers reviews your answers to decide whether Combodart is suitable.
- If approved, your Combodart capsules will be delivered discreetly to your door.
It is used to treat symptomatic benign prostatic hyperplasia (BPH), improving urine flow and reducing urinary symptoms.
One capsule per day, usually about 30 minutes after the same meal each day.
Some symptom relief (like better flow) may happen in weeks, but full benefits often take several months.
Yes. Decreased libido, erectile difficulty, or reduced ejaculation volume are common side effects of Combodart capsules.
The tamsulosin component may cause a drop in blood pressure when standing up. Rise slowly to avoid dizziness.
Yes. Combodart should not be used by women or children. Men with severe liver disease or low blood pressure need to consult before use.
It reduces prostate size while you take it. If stopped, the prostate may slowly enlarge again over time.
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Review By
GURDEV SEHMI
Last Updated On : Mar 13 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925
Authored By
GURDEV SEHMI
Last Reviewed On : Mar 23 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925


