Lantus

Lantus is used in the treatment of diabetes mellitus in adult patients, adolescents, and children from 6 years of age. Diabetes mellitus is a disease in which your body does not make enough insulin to control the level of sugar in your blood. Insulin glargine has a long and constant action of reducing blood sugar

Insulin glargine in this diabetes medication is an analogue of human insulin designed to have low solubility at neutral pH. It is completely soluble at the acidic pH of the Lantus injection solution. After injection into the subcutaneous tissue, the acidic solution is neutralized, leading to the formation of micro precipitates from which small amounts of insulin glargine are continuously released, providing a smooth and predictable concentration/time profile without peak, with a long duration of action.

Insulin glargine is metabolized into 2 active metabolites M1 and M2.

Binding to the insulin receptor: In vitro studies indicate that the affinity of insulin glargine and its metabolites M1 and M2 for the receptor for human insulin is similar to that of human insulin.

Lantus is used to reduce sugar levels in the body, its active ingredient is insulin glargine. Lantus is a long-acting drug, its presentation is in injectable solution and generally, it begins to exert its action in the body several hours after its administration and even after 24 hours of its application it can continue to work, generally this is applied in patients suffering from diabetes mellitus, as long as they are older than 6 years.

Always use this insulin medication exactly as your doctor has told you. If in doubt, consult your doctor or pharmacist again. Although Lantus contains the same active substance as Toujeo (insulin glargine 300 units/ml), these medicines are not interchangeable. Switching from one insulin treatment to another requires a prescription, medical supervision, and blood glucose control. For more information, consult your doctor.

Dose

Depending on your lifestyle and the results of your blood sugar (glucose) checks and your previous insulin treatment, your doctor will determine the dose of Lantus you need each day and at what time, It will tell you when to check your blood sugar, and if you need to have a urine test, It will tell you when you may need to inject a higher or lower dose of Lantus.

Lantus is a long-acting insulin. Your doctor may direct you to use it in combination with short-acting insulin or with tablets to treat elevated blood sugar levels.

Many factors can influence your blood sugar level. You should be aware of these factors as you will be able to react correctly to changes in your blood sugar level and prevent it from rising or falling too low.

Use in children and adolescents

Lantus can be used in adolescents and children 6 years and older. Use this medication just as your doctor has told you.

Administration frequency

You need a Lantus injection every day, always at the same time.

Administration form

Lantus is injected under the skin. DO NOT inject Lantus into a vein, as this will change its action and may cause hypoglycaemia. Your doctor will show you in which skin area you should inject Lantus. With each injection, you need to change the puncture site within the particular area of ​​skin you are using.

Like all medicines, this diabetes treatment medication can cause side effects, although not everybody gets them.

If you notice signs that your blood sugar level is too low (hypoglycemia), take immediate action to raise your blood sugar level. Hypoglycemia (low blood sugar) can be very serious and is very common during insulin treatment (it can affect more than 1 in 10 people). Low blood sugar means there is not enough blood sugar. If your blood sugar level drops too low, you may pass out (pass out). Severe hypoglycemia can damage the brain and can be life-threatening.

Common side effects (may affect up to 1 in 10 people)

• Adverse skin effects and allergic reactions at the injection site
• Signs may include redness, severe pain from the unusual injection, itching, hives, swelling, or inflammation. These reactions can spread around the injection site. Most mild insulin reactions usually go away in a few days or a few weeks.

Rare side effects (may affect up to 1 in 1,000 people)

• Eye reactions
• A significant change (improvement or worsening) in your blood sugar control can temporarily alter your vision. If you have proliferative retinopathy (a diabetes-related eye disease), severe hypoglycemic attacks can cause temporary loss of vision.

General disorders

• In rare cases, insulin treatment can also cause temporary water retention in the body, with swelling of the calves and ankles.

Very rare side effects (may affect up to 1 in 10,000 people)

• In very rare cases, dysgeusia (taste disorders) and myalgia (muscle pain) can occur.

Use in children and adolescents

In general, adverse effects in children and adolescents 18 years of age or younger are similar to those in adults.

Complaints of injection site reactions (injection site reaction, injection site pain) and skin reactions (rash, hives) have been reported more frequently in children or adolescents 18 years of age or younger than in Adults.

There is no experience in children under 6 years old.

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