Isosorbide Mononitrate
Isosorbide mononitrate is a nitrate that dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump. Isosorbide mononitrate is used to prevent angina attacks (chest pain). Isosorbide mononitrate will not treat an angina attack that has already started. The normal dose of isosorbide mononitrate is one 20 mg tablet two to three times a day. The tablets should be taken after meals without chewing and with an abundant amount of liquid (a glass of water).
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Select your preferred options and see the best price
| Pack | Price (£) | ||
|---|---|---|---|
| Chemydur | 60mg MR | 28 Tabs/Caps | 29.00 |
| Chemydur | 60mg MR | 56 Tabs/Caps | 47.00 |
| Chemydur | 60mg MR | 84 Tabs/Caps | 64.00 |
| Imdur | 60mg MR | 28 Tabs/Caps | 36.00 |
| Imdur | 60mg MR | 56 Tabs/Caps | 66.00 |
| Imdur | 60mg MR | 84 Tabs/Caps | 90.00 |
| Isib | 60mg MR | 28 Tabs/Caps | 36.00 |
| Isib | 60mg MR | 56 Tabs/Caps | 66.00 |
| Isib | 60mg MR | 84 Tabs/Caps | 90.00 |
| Isosorbide Mononitrate (generic) | 60mg MR | 28 Tabs/Caps | 24.00 |
| Isosorbide Mononitrate (generic) | 60mg MR | 56 Tabs/Caps | 42.00 |
| Isosorbide Mononitrate (generic) | 60mg MR | 84 Tabs/Caps | 48.00 |
| Monomax XL | 60mg MR | 28 Tabs/Caps | 24.00 |
| Monomax XL | 60mg MR | 56 Tabs/Caps | 42.00 |
| Monomax XL | 60mg MR | 84 Tabs/Caps | 48.00 |
| Isotard XL | 60mg MR | 28 Tabs/Caps | 24.00 |
| Isotard XL | 60mg MR | 56 Tabs/Caps | 42.00 |
| Isotard XL | 60mg MR | 84 Tabs/Caps | 48.00 |
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Chemydur 60XL Isosorbide Mononitrate for Angina Treatment
Chemydur 60XL is prescribed for adults who need reliable, day-to-day protection against angina pectoris, chest pain that happens when the heart isn't getting enough oxygen-rich blood. It's taken regularly to reduce the chance of angina episodes, rather than treating sudden pain once it starts.
Each Chemydur 60XL tablet contains isosorbide mononitrate, an extended-release nitrate medication that keeps blood vessels relaxed throughout the day. By improving blood flow and easing pressure on the heart, it supports people living with coronary artery disease and ischaemic heart disease.
If approved after an online consultation, you can purchase Chemydur 60XL from Pharmacy Planet as part of long-term cardiovascular therapy focused on heart health and everyday stability.
What Is Chemydur 60XL Isosorbide Mononitrate?
Chemydur 60XL is a modified-release tablet used to prevent angina pectoris in adults. Each tablet contains 60 mg of isosorbide mononitrate, which is released slowly over the course of the day.
Unlike short-acting nitrates that need to be taken several times daily, Chemydur 60XL is designed for once-daily dosing. This provides steady nitrate levels, helping reduce angina symptoms during normal daily activities.
It is not meant for immediate chest pain relief and is usually taken alongside a fast-acting nitrate for sudden symptoms, if needed.
How Does Chemydur 60XL Work?
Chemydur 60XL works quietly in the background to keep blood vessels relaxed and support steady angina control.
1. Extended-Release Vasodilation
The tablet releases isosorbide mononitrate gradually, keeping blood vessels open for longer periods.
2. Improves Oxygen Supply to the Heart
Wider coronary arteries allow more oxygen to reach the heart muscle affected by coronary artery disease.
3. Reduces the Heart's Workload
Relaxation of the veins and arteries lowers pressure on the heart, making everyday movement feel more manageable.
4. Prevents Angina Episodes
With regular daily use, chest pain episodes tend to occur less often across the day.
This extended-release design makes Chemydur 60XL a dependable option for long-term angina treatment.
How to Take Chemydur 60XL Isosorbide Mononitrate?
Chemydur 60XL is intended for adult use only.
Dosage Guidance:
- Usual dose: One 60 mg tablet once daily, taken in the morning.
- Dose increase: The dose may be increased to 120 mg once daily if required.
- Starting gently: Some patients may be advised to start with 30 mg daily (half a scored 60 mg tablet, if suitable) for a few days to reduce the risk of headache.
- Older adults often follow the same dosing plan, with emphasis on using the lowest effective dose.
How to Take the Tablets:
- Swallow the tablet whole with half a glass of water.
- Take it in the morning at the same time each day.
- Do not crush or chew the tablet.
- Do not stop treatment suddenly.
Who Can Use Chemydur 60XL?
Chemydur 60XL may be suitable if you:
- Have stable angina pectoris.
- Need once-daily prevention rather than multiple daily doses.
- Live with ischaemic heart disease.
- Have coronary artery disease.
- Use long-acting nitrate therapy as part of cardiovascular treatment.
Chemydur 60XL may not be suitable if you:
- Have very low blood pressure.
- Have certain heart valve or muscle conditions.
- Have raised pressure inside the skull.
- Are allergic to nitrates.
- Have severe anaemia.
- Have severe hypovolaemia.
- Use sildenafil or similar medicines.
Suitability will be confirmed by a UK prescriber during your consultation with Pharmacy Planet.
Possible Side Effects of Chemydur 60XL
Side effects are usually linked to dose strength and often settle as the body adjusts.
Common Side Effects:
- Headache, especially when starting treatment
- Dizziness
- Flushing
- Light-headedness
- Fatigue
Serious Side Effects:
- A severe drop in blood pressure
- Collapse or fainting
- Worsening chest pain
- Severe skin rashes
- Signs of an allergic reaction
If any serious side effects occur, urgent medical advice is needed.
Possible Interactions with Chemydur 60XL
Some medicines can interact with nitrate medication and increase side effects.
Do not take Chemydur 60XL with:
- Sildenafil or similar PDE-5 inhibitors.
Extra care is needed if you take:
- Blood pressure-lowering medicines.
- Calcium channel blockers.
- Diuretics.
- Alcohol.
- Certain migraine treatments.
All current medicines should be listed to your prescriber during your consultation.
Why Do People Choose Chemydur 60XL for Angina Treatment?
Chemydur 60XL is often chosen by people because of its simplicity of once-daily nitrate therapy. It also:
- Reduces how often angina occurs.
- Provides steady chest pain prevention.
- Supports managing symptoms of stable angina as part of a long-term treatment plan.
- Makes daily activity feel more manageable.
- Avoids multiple daily tablet schedules.
All this makes it a practical and reassuring option for ongoing angina management.
Consultation and Ordering from Pharmacy Planet
Getting Chemydur 60XL from Pharmacy Planet is simple and convenient.
- Complete the online consultation and answer a few questions about your heart condition and current medicines.
- A qualified UK prescriber reviews your information to confirm suitability and dosing.
- Once approved, Chemydur 60XL is dispensed and delivered discreetly to your door.
Chemydur 60XL is prescribed for adults who need reliable, day-to-day protection against angina pectoris, chest pain that happens when the heart isn't getting enough oxygen-rich blood. It's taken regularly to reduce the chance of angina episodes, rather than treating sudden pain once it starts.
Each Chemydur 60XL tablet contains isosorbide mononitrate, an extended-release nitrate medication that keeps blood vessels relaxed throughout the day. By improving blood flow and easing pressure on the heart, it supports people living with coronary artery disease and ischaemic heart disease.
If approved after an online consultation, you can purchase Chemydur 60XL from Pharmacy Planet as part of long-term cardiovascular therapy focused on heart health and everyday stability.
Chemydur 60XL is a modified-release tablet used to prevent angina pectoris in adults. Each tablet contains 60 mg of isosorbide mononitrate, which is released slowly over the course of the day.
Unlike short-acting nitrates that need to be taken several times daily, Chemydur 60XL is designed for once-daily dosing. This provides steady nitrate levels, helping reduce angina symptoms during normal daily activities.
It is not meant for immediate chest pain relief and is usually taken alongside a fast-acting nitrate for sudden symptoms, if needed.
Chemydur 60XL works quietly in the background to keep blood vessels relaxed and support steady angina control.
1. Extended-Release Vasodilation
The tablet releases isosorbide mononitrate gradually, keeping blood vessels open for longer periods.
2. Improves Oxygen Supply to the Heart
Wider coronary arteries allow more oxygen to reach the heart muscle affected by coronary artery disease.
3. Reduces the Heart's Workload
Relaxation of the veins and arteries lowers pressure on the heart, making everyday movement feel more manageable.
4. Prevents Angina Episodes
With regular daily use, chest pain episodes tend to occur less often across the day.
This extended-release design makes Chemydur 60XL a dependable option for long-term angina treatment.
Chemydur 60XL is intended for adult use only.
Dosage Guidance:
- Usual dose: One 60 mg tablet once daily, taken in the morning.
- Dose increase: The dose may be increased to 120 mg once daily if required.
- Starting gently: Some patients may be advised to start with 30 mg daily (half a scored 60 mg tablet, if suitable) for a few days to reduce the risk of headache.
- Older adults often follow the same dosing plan, with emphasis on using the lowest effective dose.
How to Take the Tablets:
- Swallow the tablet whole with half a glass of water.
- Take it in the morning at the same time each day.
- Do not crush or chew the tablet.
- Do not stop treatment suddenly.
Chemydur 60XL may be suitable if you:
- Have stable angina pectoris.
- Need once-daily prevention rather than multiple daily doses.
- Live with ischaemic heart disease.
- Have coronary artery disease.
- Use long-acting nitrate therapy as part of cardiovascular treatment.
Chemydur 60XL may not be suitable if you:
- Have very low blood pressure.
- Have certain heart valve or muscle conditions.
- Have raised pressure inside the skull.
- Are allergic to nitrates.
- Have severe anaemia.
- Have severe hypovolaemia.
- Use sildenafil or similar medicines.
Suitability will be confirmed by a UK prescriber during your consultation with Pharmacy Planet.
Side effects are usually linked to dose strength and often settle as the body adjusts.
Common Side Effects:
- Headache, especially when starting treatment
- Dizziness
- Flushing
- Light-headedness
- Fatigue
Serious Side Effects:
- A severe drop in blood pressure
- Collapse or fainting
- Worsening chest pain
- Severe skin rashes
- Signs of an allergic reaction
If any serious side effects occur, urgent medical advice is needed.
Some medicines can interact with nitrate medication and increase side effects.
Do not take Chemydur 60XL with:
- Sildenafil or similar PDE-5 inhibitors.
Extra care is needed if you take:
- Blood pressure-lowering medicines.
- Calcium channel blockers.
- Diuretics.
- Alcohol.
- Certain migraine treatments.
All current medicines should be listed to your prescriber during your consultation.
Chemydur 60XL is often chosen by people because of its simplicity of once-daily nitrate therapy. It also:
- Reduces how often angina occurs.
- Provides steady chest pain prevention.
- Supports managing symptoms of stable angina as part of a long-term treatment plan.
- Makes daily activity feel more manageable.
- Avoids multiple daily tablet schedules.
All this makes it a practical and reassuring option for ongoing angina management.
Getting Chemydur 60XL from Pharmacy Planet is simple and convenient.
- Complete the online consultation and answer a few questions about your heart condition and current medicines.
- A qualified UK prescriber reviews your information to confirm suitability and dosing.
- Once approved, Chemydur 60XL is dispensed and delivered discreetly to your door.
Isosorbide mononitrate contains isosorbide mononitrate as the active substance, which belongs to a group of medicines known as nitrates that have vasodilatory properties of the coronary arteries of the heart (arteries that supply the heart muscle tissue).
Isosorbide mononitrate is a coronary vasodilator and is the main active metabolite of dinitrate of isosorbide, which is presented as a single substance in isosorbide mononitrate. The Isosorbide mononitrate lacks the hepatic first-pass effect, therefore its pharmacokinetics different from that of isosorbide dinitrate. Isosorbide mononitrate is characterized by the following pharmacological properties:
- Direct relaxation of the vascular smooth musculature.
- Increased vessel capacity ("venous pooling").
- Decreased blood return to the heart.
- Reduction of central venous pressure.
- Reduction of the tension of the ventricular walls.
- Dilation of the great arteries which leads to a reduction in vascular resistance
- systemic and pulmonary.
- Increased functional performance of the great arteries ("wind vessel" effect).
Isosorbide mononitrate uses include being indicated for the treatment and prevention of angina pectoris (chest pain and tightness that occurs when not enough blood reaches the heart).
The best time and way to take Isosorbide mononitrate is exactly as your doctor has told you. Ask your doctor or pharmacist if you have doubts. The normal dose of isosorbide mononitrate is one 20 mg tablet two to three times a day. The tablets should be taken after meals without chewing and with an abundant amount of liquid (a glass of water). The tablets are scored and can be easily divided into two halves to allow dose adjustment. If the response obtained is not sufficient, the dose can be increased up to 40 mg (two tablets) two or three times a day. In patients not used to nitrate treatment, and to prevent or minimize possible headache, your doctor will recommend starting with a low dose (for example, half a tablet of Isosorbide Mononitrate 20 mg, twice a day). per day), which will be gradually increased later. If you think the action of Isosorbide Mononitrate 20 mg tablets is too strong or weak, please inform your doctor or pharmacist. During therapy with Isosorbide Mononitrate tolerance may develop (decrease effect). It is recommended to keep the dose as low as possible and allow a maximum possible time interval between doses to regain sensitivity (first dose in the morning and last dose in the late afternoon). You should take this medication while sitting, especially at the beginning of treatment, if you are taking high doses or if you are over 65 years of age. It is important that you start and stop treatment with Isosorbide Mononitrate gradually and never abruptly. Your doctor will tell you how to gradually increase and decrease the dose. Your doctor will indicate the duration of your treatment with this medicine. Do not stop the treatment sooner as there could be a sudden increase in tension.
Like all medicines, Isosorbide Mononitrate NORMON can have side effects, although not everybody gets them. During the period of use of Isosorbide Mononitrate, the following side effects have been observed, the frequency of which cannot be established with accuracy. In certain cases, especially at high doses, or at the beginning of treatment, orthostatic hypotension (feeling dizzy on rising) may occur. In especially sensitive patients, hypotension can lead to syncope (fainting), which may be confused, by symptoms, with acute myocardial infarction. Occasionally, and especially when first used, gastrointestinal complaints such as nausea and/or vomiting may appear. In patients with a history of coronary heart disease (narrowing of the arteries to the heart), ischemia (transient or permanent decrease in blood supply) may occur. In patients with methemoglobin reductase deficiency or with abnormal hemoglobin structure, a blood alteration may occur (formation of methemoglobin), which results in a lower content of oxygen in the blood, which may produce bluish discoloration of the skin and mucous membranes, pain headache, fatigue, shortness of breath and lack of energy. Rarely, it can cause skin rashes and / or exfoliative dermatitis (peeling of the skin). Other adverse effects are headache, flushing, or warm facial sensation, dizziness, palpitations, fatigue. In general, all these effects, including hypotension, disappear with continued treatment or, in any case, with decreasing the dose.
You can buy the isosorbide mononitrate medication online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy this heart medicine online, use Pharmacy Planet, a UK pharmacy you can trust.
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Review By
GURDEV SEHMI
Last Updated On : Mar 13 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925
Authored By
GURDEV SEHMI
Last Reviewed On : Mar 23 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925


