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Synalar Cream | Fluocinolone Acetonide Corticosteroid for Eczema & Psoriasis

Synalar is a hormonal treatment whose active ingredient is fluocinolone acetonide, which is a type of medicine known as a topical corticosteroid (the hormone from the adrenal cortex). Synalar is used to reduce inflammation and relieve symptoms such as itching, pain, peeling, redness, and swelling. Synalar cream, ointment, or gel should be applied sparingly and evenly to the affected area (s). Avoid contact with the eyes and wash your hands thoroughly after each application. Do not cover the treated area (s) with bandages or other dressings unless your doctor tells you otherwise (note that children's diapers can also function as occlusive bandages).

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Synalar Cream | Fluocinolone Acetonide Corticosteroid for Eczema & Psoriasis
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Please note that whilst you are able to request the medicine strength and size required,
we will only be able to send on approval from our in house pharmacist.

Starts at £25.00
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Price Comparison

Select your preferred options and see the best price

Pack Price (£)
Cream 0.025% - 30g x 1 Tube 25.00
Cream 0.025% - 30g x 2 Tubes 40.00
Ointment 0.025% - 30g x 1 Tube 25.00
Ointment 0.025% - 30g x 2 Tubes 40.00
Gel 0.025% - 30g x 1 Tube 25.00
Gel 0.025% - 30g x 2 Tubes 40.00

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Synalar Cream (Fluocinolone Acetonide) for Eczema and Psoriasis Treatment

Skin flare-ups can come on quickly; one day your skin feels manageable, and the next it's red, itchy, and uncomfortable. When this happens, having a treatment that works fast without being overly aggressive is important.

Synalar cream is commonly used during these moments. Containing fluocinolone acetonide, it is a mild-to-moderate steroid designed to calm inflammation and bring relief to irritated skin. As a trusted eczema steroid, it is widely used for short-term dermatitis treatment and targeted psoriasis flare control.

What Is Synalar Cream (Fluocinolone Acetonide) Used For?

Synalar cream is a topical steroid treatment used for inflammatory skin conditions. It is commonly prescribed for:

  • Eczema flare-ups and itching.
  • Contact or allergic dermatitis.
  • Small areas of psoriasis.
  • Red, inflamed, or irritated skin patches.

As a rash steroid cream, it focuses on reducing visible symptoms while improving skin comfort.

How Synalar Cream Works on Skin Inflammation

Synalar works by calming the immune response in the skin. The active ingredient, fluocinolone acetonide, is a corticosteroid that:

  • Reduces inflammation and swelling.
  • Eases itching and irritation.
  • Controls redness during flare-ups.

In conditions like eczema and dermatitis, the skin reacts strongly to triggers. This anti-inflammatory cream interrupts that response, allowing the skin to settle and recover.

How to Use Synalar Cream Safely

Using Synalar correctly ensures effective results with minimal risk. Typical instructions include:

  • Apply a thin layer once or twice daily.
  • Gently rub into the affected area.
  • Use only on irritated skin.
  • Wash your hands after application.

Important usage advice: Do not use for more than 7 days unless advised. Avoid applying to large areas of the body. Do not apply to the face unless directed. Do not use on infected skin. If symptoms do not improve or worsen, treatment should be reviewed.

Who Can Use Synalar Cream?

Synalar may be suitable for:

  • Adults with eczema or dermatitis.
  • Individuals with small psoriasis patches.
  • Children (lower strengths under supervision).

A prescriber will confirm whether this mild-to-moderate steroid is suitable for your condition.

Who Should Not Use Synalar Cream

Synalar is not suitable in certain situations. You should avoid using it if you:

  • Have untreated skin infections.
  • Have acne or rosacea.
  • Are applying to broken or damaged skin.
  • Have had reactions to steroid creams before.

Using it incorrectly may worsen certain skin conditions.

Possible Side Effects of Synalar Cream

Side effects are usually mild when Synalar cream is used correctly and for short periods. Most people do not experience any serious problems.

Common side effects:

These are usually mild and may happen when you first start using the cream:

  • A mild burning or stinging feeling after application.
  • Slight skin irritation or sensitivity.
  • Temporary redness at the application site.

These effects often settle within a few days as your skin adjusts to the treatment.

Serious side effects:

These are more likely if the cream is used for long periods or on large areas of skin:

  • Thinning of the skin, making it more fragile.
  • Stretch marks, especially in areas where the skin folds.
  • Changes in skin colour, such as lightening or darkening.
  • Increased hair growth in the treated area.
  • In rare cases, long-term use may allow small amounts of the steroid to enter the bloodstream, increasing the risk of wider side effects.

If your skin becomes worse, develops a rash, or shows signs of infection, stop using the cream and seek medical advice.

Possible Interactions and Precautions

Some precautions are important when using Synalar. Be cautious if you:

  • Use other steroid treatments at the same time.
  • Apply to large areas of skin.
  • Use under bandages or coverings.

Avoid exposure to naked flames after application, as some ingredients can make fabrics more flammable.

When Is Synalar Cream the Right Choice?

Synalar is usually recommended when:

  • Symptoms are mild to moderate.
  • You need a balanced eczema steroid option.
  • You want targeted psoriasis flare control.
  • Stronger steroids are not necessary.

It is often used as a short-term solution during flare-ups.

How Synalar Cream Fits into Long-Term Skin Care

Synalar is typically part of a broader skincare routine. It is often combined with:

  • Regular moisturisers to maintain hydration.
  • Avoidance of known triggers.
  • Step-down or step-up treatments depending on symptoms.

Using Synalar correctly supports consistent skin control without overuse of stronger treatments.

Why Do People Choose Synalar Cream?

Synalar is often chosen for balanced and controlled treatment. People choose Synalar because:

  • It provides effective skin inflammation relief.
  • It is suitable for short-term flare-up control.
  • It works well for both eczema and psoriasis patches.
  • It is a reliable topical option for recurring symptoms.
  • It offers a middle ground between mild and stronger steroids.
  • It is particularly useful when symptoms are noticeable but do not require very strong treatments.

Topical Steroid Treatments for Eczema & Psoriasis

Topical steroids are used to reduce inflammation, redness, and itching in skin conditions such as eczema and psoriasis. They come in different strengths, and the right option depends on the severity and area being treated.

ProductWhat it isWhat it's mainly used forStrength (general)How you usually use itWhat to expect
HydrocortisoneMild steroid creamMild eczema, irritationMildApplied once or twice dailyGentle option. Suitable for sensitive areas like the face.
Eumovate OintmentModerate steroid (clobetasone)Mild to moderate eczemaModerateApplied once or twice dailyHelps reduce redness and itching.
Betnovate (Betamethasone)Potent steroidModerate to severe eczema/psoriasisPotentApplied once or twice dailyStronger effect. Usually used for short periods.
Elocon CreamPotent steroid (mometasone)Eczema and psoriasisPotentApplied once dailyLong-lasting effect. Helps reduce flare-ups.
Cutivate OintmentPotent steroid (fluticasone)Eczema and dermatitisPotentApplied once or twice dailyHelps calm inflamed skin.
Synalar CreamSteroid (fluocinolone)Inflammatory skin conditionsModerate to potentApplied as prescribedReduces swelling and itching.
Dermovate CreamVery potent steroid (clobetasol)Severe eczema or psoriasisVery potentUsed for short periods onlyVery strong. Used when other treatments are not enough.

Important: This comparison is for general information only and does not replace medical advice. A prescriber will decide which treatment is suitable for you following an online consultation.

How Does the Ordering Process Work at Pharmacy Planet?

Getting started with Synalar cream is simple and designed around your routine.

  1. Complete an Online Consultation — Share details about your skin condition, symptoms, and current treatments.
  2. Prescriber Review — A UK-registered prescriber checks if Synalar is suitable for your condition.
  3. Discreet Delivery — If approved, Synalar is dispensed and delivered securely to your chosen address.
Synalar Cream

Skin flare-ups can come on quickly; one day your skin feels manageable, and the next it's red, itchy, and uncomfortable. When this happens, having a treatment that works fast without being overly aggressive is important.

Synalar cream is commonly used during these moments. Containing fluocinolone acetonide, it is a mild-to-moderate steroid designed to calm inflammation and bring relief to irritated skin. As a trusted eczema steroid, it is widely used for short-term dermatitis treatment and targeted psoriasis flare control.

Synalar cream is a topical steroid treatment used for inflammatory skin conditions. It is commonly prescribed for:

  • Eczema flare-ups and itching.
  • Contact or allergic dermatitis.
  • Small areas of psoriasis.
  • Red, inflamed, or irritated skin patches.

As a rash steroid cream, it focuses on reducing visible symptoms while improving skin comfort.

Synalar works by calming the immune response in the skin. The active ingredient, fluocinolone acetonide, is a corticosteroid that:

  • Reduces inflammation and swelling.
  • Eases itching and irritation.
  • Controls redness during flare-ups.

In conditions like eczema and dermatitis, the skin reacts strongly to triggers. This anti-inflammatory cream interrupts that response, allowing the skin to settle and recover.

Using Synalar correctly ensures effective results with minimal risk. Typical instructions include:

  • Apply a thin layer once or twice daily.
  • Gently rub into the affected area.
  • Use only on irritated skin.
  • Wash your hands after application.

Important usage advice: Do not use for more than 7 days unless advised. Avoid applying to large areas of the body. Do not apply to the face unless directed. Do not use on infected skin. If symptoms do not improve or worsen, treatment should be reviewed.

Synalar may be suitable for:

  • Adults with eczema or dermatitis.
  • Individuals with small psoriasis patches.
  • Children (lower strengths under supervision).

A prescriber will confirm whether this mild-to-moderate steroid is suitable for your condition.

Synalar is not suitable in certain situations. You should avoid using it if you:

  • Have untreated skin infections.
  • Have acne or rosacea.
  • Are applying to broken or damaged skin.
  • Have had reactions to steroid creams before.

Using it incorrectly may worsen certain skin conditions.

Side effects are usually mild when Synalar cream is used correctly and for short periods. Most people do not experience any serious problems.

Common side effects:

These are usually mild and may happen when you first start using the cream:

  • A mild burning or stinging feeling after application.
  • Slight skin irritation or sensitivity.
  • Temporary redness at the application site.

These effects often settle within a few days as your skin adjusts to the treatment.

Serious side effects:

These are more likely if the cream is used for long periods or on large areas of skin:

  • Thinning of the skin, making it more fragile.
  • Stretch marks, especially in areas where the skin folds.
  • Changes in skin colour, such as lightening or darkening.
  • Increased hair growth in the treated area.
  • In rare cases, long-term use may allow small amounts of the steroid to enter the bloodstream, increasing the risk of wider side effects.

If your skin becomes worse, develops a rash, or shows signs of infection, stop using the cream and seek medical advice.

Some precautions are important when using Synalar. Be cautious if you:

  • Use other steroid treatments at the same time.
  • Apply to large areas of skin.
  • Use under bandages or coverings.

Avoid exposure to naked flames after application, as some ingredients can make fabrics more flammable.

Synalar is usually recommended when:

  • Symptoms are mild to moderate.
  • You need a balanced eczema steroid option.
  • You want targeted psoriasis flare control.
  • Stronger steroids are not necessary.

It is often used as a short-term solution during flare-ups.

Synalar is typically part of a broader skincare routine. It is often combined with:

  • Regular moisturisers to maintain hydration.
  • Avoidance of known triggers.
  • Step-down or step-up treatments depending on symptoms.

Using Synalar correctly supports consistent skin control without overuse of stronger treatments.

Synalar is often chosen for balanced and controlled treatment. People choose Synalar because:

  • It provides effective skin inflammation relief.
  • It is suitable for short-term flare-up control.
  • It works well for both eczema and psoriasis patches.
  • It is a reliable topical option for recurring symptoms.
  • It offers a middle ground between mild and stronger steroids.
  • It is particularly useful when symptoms are noticeable but do not require very strong treatments.

Topical Steroid Treatments for Eczema & Psoriasis

Topical steroids are used to reduce inflammation, redness, and itching in skin conditions such as eczema and psoriasis. They come in different strengths, and the right option depends on the severity and area being treated.

ProductWhat it isWhat it's mainly used forStrength (general)How you usually use itWhat to expect
HydrocortisoneMild steroid creamMild eczema, irritationMildApplied once or twice dailyGentle option. Suitable for sensitive areas like the face.
Eumovate OintmentModerate steroid (clobetasone)Mild to moderate eczemaModerateApplied once or twice dailyHelps reduce redness and itching.
Betnovate (Betamethasone)Potent steroidModerate to severe eczema/psoriasisPotentApplied once or twice dailyStronger effect. Usually used for short periods.
Elocon CreamPotent steroid (mometasone)Eczema and psoriasisPotentApplied once dailyLong-lasting effect. Helps reduce flare-ups.
Cutivate OintmentPotent steroid (fluticasone)Eczema and dermatitisPotentApplied once or twice dailyHelps calm inflamed skin.
Synalar CreamSteroid (fluocinolone)Inflammatory skin conditionsModerate to potentApplied as prescribedReduces swelling and itching.
Dermovate CreamVery potent steroid (clobetasol)Severe eczema or psoriasisVery potentUsed for short periods onlyVery strong. Used when other treatments are not enough.

Important: This comparison is for general information only and does not replace medical advice. A prescriber will decide which treatment is suitable for you following an online consultation.

Getting started with Synalar cream is simple and designed around your routine.

  1. Complete an Online Consultation — Share details about your skin condition, symptoms, and current treatments.
  2. Prescriber Review — A UK-registered prescriber checks if Synalar is suitable for your condition.
  3. Discreet Delivery — If approved, Synalar is dispensed and delivered securely to your chosen address.
Frequently Asked Questions

Synalar cream is used to treat eczema, dermatitis, and small areas of psoriasis. It reduces redness, itching, and inflammation during skin flare-ups.

Synalar is a mild-to-moderate steroid, depending on the strength prescribed. It sits between very mild creams like hydrocortisone and stronger prescription steroids.

Most people notice less itching and redness within a few days. Skin usually starts to settle within a week if the treatment is working well.

It is not usually recommended for the face unless specifically advised, as facial skin is thinner and more sensitive to steroid creams.

It is typically applied once or twice a day in a thin layer. Using more than needed will not make it work faster.

If your skin does not improve within 7 days or gets worse, the treatment may need to be reviewed and adjusted.

Yes, it can be used for small areas of psoriasis, especially during flare-ups. It is not usually used for large or widespread psoriasis.

Yes, moisturisers are important. Apply moisturiser first, wait around 10–15 minutes, then apply Synalar so it absorbs properly.

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Review By

GURDEV SEHMI

Last Updated On : Mar 13 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925

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Authored By

GURDEV SEHMI

Last Reviewed On : Mar 23 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925