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Asacol/Mesalazine

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Asacol/Mesalazine
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Please note that whilst you are able to request the medicine strength and size required,
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Starts at £59.00
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Price Comparison

Select your preferred options and see the best price

Pack Price (£)
Asacol MR 400mg 168 Tablets 107.00
Asacol MR 400mg 252 Tablets 149.00
Asacol MR 400mg 84 Tablets 59.00
Asacol MR 800mg 168 Tablets 171.00
Asacol MR 800mg 252 Tablets 240.00
Asacol MR 800mg 84 Tablets 95.00

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Asacol Tablets | Mesalazine Anti-Inflammatory for Ulcerative Colitis

Living with ongoing gut inflammation can feel exhausting, from frequent bathroom trips to persistent abdominal discomfort. Asacol / Mesalazine tablets are widely used to treat ulcerative colitis and other inflammatory bowel conditions by targeting inflammation directly in the gut.

As a trusted prescription bowel medication, Mesalazine focuses on healing the lining of the intestine, supporting long-term digestive care and improving overall colon health.

What Are Asacol / Mesalazine Tablets Used For?

Mesalazine tablets are used to treat inflammatory bowel conditions, especially ulcerative colitis. This medicine is commonly prescribed for:

  • Ulcerative colitis flare-ups.
  • Maintaining remission in chronic bowel conditions.
  • Other forms of inflammatory bowel disease.
  • Managing symptoms linked to gut inflammation.

Although often associated with IBS, Mesalazine is primarily used where inflammation is the main cause of symptoms rather than muscle spasms.

How Asacol / Mesalazine Tablets Work in the Gut

Mesalazine tablets work by reducing inflammation in the lining of the bowel. Unlike antispasmodics, Mesalazine acts as an anti-inflammatory gut treatment, targeting swelling and irritation directly. It works by:

  • Reducing inflammation in the colon.
  • Protecting the intestinal lining.
  • Supporting healing of damaged tissue.
  • Preventing flare-ups when used regularly.

This makes it an important option in long-term bowel therapy for inflammatory conditions.

How to Take Asacol / Mesalazine Tablets

Mesalazine tablets should be taken exactly as prescribed to ensure proper release in the gut.

General guidance:

  • Swallow tablets whole with water.
  • Do not crush or chew the tablets.
  • Follow your prescribed dosing schedule.

Typical use: Taken once daily or split into multiple doses. Dose may change depending on symptom severity. Lower maintenance doses may be used after improvement.

Important tips: Drink plenty of fluids throughout the day. Leave a gap if taking indigestion remedies.

Taking the medicine correctly ensures it reaches the colon where it is most effective.

Who Can Use Asacol / Mesalazine Tablets?

Mesalazine tablets are suitable for many patients with inflammatory bowel conditions, under medical supervision. They may be prescribed for:

  • Adults with ulcerative colitis.
  • Children over a certain age, depending on clinical advice.
  • Patients needing long-term bowel therapy.

Your prescriber will determine if this prescription bowel medication is right for your condition.

Who Should Not Take Asacol / Mesalazine Tablets?

It may not be suitable for people with certain health conditions or sensitivities. Avoid or take extra care if you:

  • Are allergic to Mesalazine or similar medicines.
  • Have kidney or liver problems.
  • Have previously experienced severe reactions to similar treatments.
  • Are pregnant or breastfeeding without medical advice.

A consultation ensures safe and appropriate gastrointestinal treatment.

Possible Side Effects of Asacol / Mesalazine Tablets

Like all medicines, Asacol / Mesalazine tablets can cause side effects, although many people tolerate them well.

Common side effects:

  • Stomach pain or discomfort.
  • Indigestion or wind.
  • Nausea or vomiting.
  • Headaches.

Serious side effects:

  • Severe skin reactions or rashes.
  • Signs of infection such as fever or sore throat.
  • Changes in urine or kidney-related symptoms.
  • Liver-related symptoms such as yellowing of skin or eyes.

Seek medical advice immediately if any serious symptoms occur.

Possible Interactions with Asacol / Mesalazine Tablets

Mesalazine tablets can interact with medicines that affect kidney function or blood clotting. Tell your prescriber if you are taking:

  • Anti-inflammatory painkillers (NSAIDs).
  • Medicines affecting the immune system.
  • Blood-thinning medications.
  • Laxatives or digestive treatments.

This prevents complications and ensures effective digestive care.

Important Advice Before Taking Asacol / Mesalazine Tablets

You will usually need monitoring before and during treatment with Mesalazine tablets. Before starting, your prescriber may suggest:

  • Blood tests.
  • Kidney and liver function tests.

During treatment:

  • Regular check-ups may be required.
  • Stay well hydrated to support kidney function.

This ensures safe and effective long-term bowel therapy.

Why Do People Choose Asacol / Mesalazine Tablets?

People choose Asacol / Mesalazine tablets for consistent control of inflammation and long-term digestive stability. It is commonly selected because:

  • It targets the root cause of ulcerative colitis.
  • It supports both treatment and maintenance phases.
  • It improves daily comfort and bowel function.
  • It plays a key role in structured digestive care plans.

For patients managing chronic conditions, it offers a reliable and clinically established approach to colon health.

Mesalazine & Bowel Inflammation Treatments

These medicines are used to reduce inflammation in the bowel and are commonly prescribed for inflammatory bowel conditions such as ulcerative colitis. The table below compares commonly prescribed bowel inflammation treatments and how they are typically used.

ProductWhat it isWhat it's mainly used forHow you usually use itWhat to expect
Asacol / Mesalazine TabletsMesalazine anti-inflammatory tabletsUlcerative colitis and bowel inflammationTaken regularly as prescribedHelps reduce inflammation inside the bowel.
Mezavant / Mesalazine TabletsLong-acting mesalazine tabletsUlcerative colitisTaken once dailyDesigned for slow release throughout the bowel.
Octasa / Mesalazine TabletsMesalazine tabletsInflammatory bowel conditionsTaken regularlyHelps maintain symptom control and reduce flare-ups.
Pentasa / Mesalazine TabletsMesalazine tabletsBowel inflammationTaken regularlySlow-release treatment for ongoing inflammation control.
Pentasa / Mesalazine SachetsMesalazine granule sachetsUlcerative colitis and bowel inflammationTaken as prescribedSachet form may be easier for some people than tablets.
Salofalk / Mesalazine TabletsMesalazine tabletsInflammatory bowel diseaseTaken regularlyHelps manage bowel inflammation over time.
Salofalk / Mesalazine SachetsMesalazine granule sachetsBowel inflammationTaken as prescribedGranule form designed for bowel delivery.
Colazide / Balsalazide CapsulesAnti-inflammatory bowel capsulesUlcerative colitisTaken regularlyTargets inflammation in the large bowel.
OlsalazineAnti-inflammatory bowel medicineUlcerative colitisTaken regularlyHelps reduce bowel inflammation and maintain remission.
Sulfasalazine / Salazopyrin TabletsAnti-inflammatory bowel tabletsUlcerative colitis and inflammatory bowel conditionsTaken regularlyHelps control bowel inflammation and symptoms.

Important: This comparison is for general information only and does not replace medical advice. A prescriber will decide which treatment is suitable for you following an online consultation.

How to Order Asacol / Mesalazine Tablets Online from Pharmacy Planet

Ordering Mesalazine tablets is simple and secure.

  1. Complete an Online Consultation — Provide details about your symptoms and health.
  2. Prescription Review — A UK-registered prescriber confirms if Mesalazine tablets are suitable.
  3. Discreet Delivery — If approved, your treatment is delivered directly to your chosen address.
Asacol/Mesalazine Tablets

Living with ongoing gut inflammation can feel exhausting, from frequent bathroom trips to persistent abdominal discomfort. Asacol / Mesalazine tablets are widely used to treat ulcerative colitis and other inflammatory bowel conditions by targeting inflammation directly in the gut.

As a trusted prescription bowel medication, Mesalazine focuses on healing the lining of the intestine, supporting long-term digestive care and improving overall colon health.

Mesalazine tablets are used to treat inflammatory bowel conditions, especially ulcerative colitis. This medicine is commonly prescribed for:

  • Ulcerative colitis flare-ups.
  • Maintaining remission in chronic bowel conditions.
  • Other forms of inflammatory bowel disease.
  • Managing symptoms linked to gut inflammation.

Although often associated with IBS, Mesalazine is primarily used where inflammation is the main cause of symptoms rather than muscle spasms.

Mesalazine tablets work by reducing inflammation in the lining of the bowel. Unlike antispasmodics, Mesalazine acts as an anti-inflammatory gut treatment, targeting swelling and irritation directly. It works by:

  • Reducing inflammation in the colon.
  • Protecting the intestinal lining.
  • Supporting healing of damaged tissue.
  • Preventing flare-ups when used regularly.

This makes it an important option in long-term bowel therapy for inflammatory conditions.

Mesalazine tablets should be taken exactly as prescribed to ensure proper release in the gut.

General guidance:

  • Swallow tablets whole with water.
  • Do not crush or chew the tablets.
  • Follow your prescribed dosing schedule.

Typical use: Taken once daily or split into multiple doses. Dose may change depending on symptom severity. Lower maintenance doses may be used after improvement.

Important tips: Drink plenty of fluids throughout the day. Leave a gap if taking indigestion remedies.

Taking the medicine correctly ensures it reaches the colon where it is most effective.

Mesalazine tablets are suitable for many patients with inflammatory bowel conditions, under medical supervision. They may be prescribed for:

  • Adults with ulcerative colitis.
  • Children over a certain age, depending on clinical advice.
  • Patients needing long-term bowel therapy.

Your prescriber will determine if this prescription bowel medication is right for your condition.

It may not be suitable for people with certain health conditions or sensitivities. Avoid or take extra care if you:

  • Are allergic to Mesalazine or similar medicines.
  • Have kidney or liver problems.
  • Have previously experienced severe reactions to similar treatments.
  • Are pregnant or breastfeeding without medical advice.

A consultation ensures safe and appropriate gastrointestinal treatment.

Like all medicines, Asacol / Mesalazine tablets can cause side effects, although many people tolerate them well.

Common side effects:

  • Stomach pain or discomfort.
  • Indigestion or wind.
  • Nausea or vomiting.
  • Headaches.

Serious side effects:

  • Severe skin reactions or rashes.
  • Signs of infection such as fever or sore throat.
  • Changes in urine or kidney-related symptoms.
  • Liver-related symptoms such as yellowing of skin or eyes.

Seek medical advice immediately if any serious symptoms occur.

Mesalazine tablets can interact with medicines that affect kidney function or blood clotting. Tell your prescriber if you are taking:

  • Anti-inflammatory painkillers (NSAIDs).
  • Medicines affecting the immune system.
  • Blood-thinning medications.
  • Laxatives or digestive treatments.

This prevents complications and ensures effective digestive care.

You will usually need monitoring before and during treatment with Mesalazine tablets. Before starting, your prescriber may suggest:

  • Blood tests.
  • Kidney and liver function tests.

During treatment:

  • Regular check-ups may be required.
  • Stay well hydrated to support kidney function.

This ensures safe and effective long-term bowel therapy.

People choose Asacol / Mesalazine tablets for consistent control of inflammation and long-term digestive stability. It is commonly selected because:

  • It targets the root cause of ulcerative colitis.
  • It supports both treatment and maintenance phases.
  • It improves daily comfort and bowel function.
  • It plays a key role in structured digestive care plans.

For patients managing chronic conditions, it offers a reliable and clinically established approach to colon health.

Mesalazine & Bowel Inflammation Treatments

These medicines are used to reduce inflammation in the bowel and are commonly prescribed for inflammatory bowel conditions such as ulcerative colitis. The table below compares commonly prescribed bowel inflammation treatments and how they are typically used.

ProductWhat it isWhat it's mainly used forHow you usually use itWhat to expect
Asacol / Mesalazine TabletsMesalazine anti-inflammatory tabletsUlcerative colitis and bowel inflammationTaken regularly as prescribedHelps reduce inflammation inside the bowel.
Mezavant / Mesalazine TabletsLong-acting mesalazine tabletsUlcerative colitisTaken once dailyDesigned for slow release throughout the bowel.
Octasa / Mesalazine TabletsMesalazine tabletsInflammatory bowel conditionsTaken regularlyHelps maintain symptom control and reduce flare-ups.
Pentasa / Mesalazine TabletsMesalazine tabletsBowel inflammationTaken regularlySlow-release treatment for ongoing inflammation control.
Pentasa / Mesalazine SachetsMesalazine granule sachetsUlcerative colitis and bowel inflammationTaken as prescribedSachet form may be easier for some people than tablets.
Salofalk / Mesalazine TabletsMesalazine tabletsInflammatory bowel diseaseTaken regularlyHelps manage bowel inflammation over time.
Salofalk / Mesalazine SachetsMesalazine granule sachetsBowel inflammationTaken as prescribedGranule form designed for bowel delivery.
Colazide / Balsalazide CapsulesAnti-inflammatory bowel capsulesUlcerative colitisTaken regularlyTargets inflammation in the large bowel.
OlsalazineAnti-inflammatory bowel medicineUlcerative colitisTaken regularlyHelps reduce bowel inflammation and maintain remission.
Sulfasalazine / Salazopyrin TabletsAnti-inflammatory bowel tabletsUlcerative colitis and inflammatory bowel conditionsTaken regularlyHelps control bowel inflammation and symptoms.

Important: This comparison is for general information only and does not replace medical advice. A prescriber will decide which treatment is suitable for you following an online consultation.

Ordering Mesalazine tablets is simple and secure.

  1. Complete an Online Consultation — Provide details about your symptoms and health.
  2. Prescription Review — A UK-registered prescriber confirms if Mesalazine tablets are suitable.
  3. Discreet Delivery — If approved, your treatment is delivered directly to your chosen address.
Frequently Asked Questions

Asacol starts working from the first dose, but noticeable improvement usually takes a few weeks. Full control of inflammation may take longer with regular use.

Yes, it is often used to control flare-ups and keep symptoms stable. It reduces inflammation in the bowel, which lowers the chances of symptoms coming back.

The tablets have a special coating that protects the medicine until it reaches your gut. Breaking or chewing them stops the medicine from working properly.

In rare cases, it can affect kidney function. This is why regular blood and urine tests are done to make sure your body is handling the medicine safely.

If your symptoms continue or get worse, speak to your prescriber. Your dose may need adjusting, or another treatment may be added to your plan.

You should leave a gap between them. Indigestion remedies can affect how well Mesalazine is absorbed and reduce its effectiveness.

Yes, by reducing inflammation in the bowel, it can improve diarrhoea linked to ulcerative colitis and make bowel movements more manageable.

Alcohol does not directly interact, but it can irritate your gut and worsen symptoms. It is best to limit alcohol, especially during flare-ups.

Yes, many people continue taking it even when symptoms improve. This maintenance use prevents inflammation from returning and keeps your condition stable.

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Review By

HARMINDER ‘HARMY’ KAUR

Last Updated On : Mar 13 2026

BSc(hons) Pharmacy

GPhC Number: 2061107

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Authored By

GURDEV SEHMI

Last Reviewed On : Mar 23 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925