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Colazide Balsalazide is a prodrug of 5-aminosalicylic acid (also known as mesalazine) that hydrolyzes in the intestine, causing the active drug that has anti-inflammatory properties. Colazide Balsalazide comes as a capsule that is to be taken orally. It is generally taken 3 times a day. Carefully follow the directions on the medicine label and ask your doctor or pharmacist anything you don't understand. Use the medication exactly as directed. Do not use more or less than the indicated dose or more often than prescribed by your doctor. Colazide Balsalazide is generally taken for 8 weeks but can be taken for up to 12. Continue taking the medication even if you feel better, and do not stop taking it without first talking to your doctor.

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Price Comparison

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Pack Price (£)
Colazide 750mg 130 capsules 88.00
Colazide 750mg 260 capsules 152.00
Colazide 750mg 390 capsules 234.00

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Colazide Capsules | Balsalazide 5-ASA Prodrug for Ulcerative Colitis

Living with ongoing bowel discomfort, urgency, or frequent diarrhoea can quickly take over your day. Colazide / Balsalazide Capsules are designed for people dealing with inflammation in the bowel, offering targeted relief where it matters most.

This prescription bowel therapy works directly in the colon to reduce irritation, calm symptoms, and support long-term gut health. Unlike general digestive treatments, Colazide focuses on the root cause – inflammation in the lining of the bowel. This makes it a trusted option for ulcerative colitis relief and ongoing bowel care when symptoms keep returning.

What Are Colazide / Balsalazide Capsules?

Colazide capsules contain balsalazide, a type of anti-inflammatory gut medicine used to treat conditions affecting the large intestine. It belongs to a group of medicines commonly used in bowel inflammation treatment.

Once taken, balsalazide travels to the colon, where it releases its active component. This targeted action supports healing in the affected area without unnecessary impact on the rest of the body. This makes it suitable for:

  • Ulcerative colitis treatment.
  • Long-term colon inflammation treatment.
  • Managing recurring bowel symptoms.
  • Supporting digestive health in inflammatory conditions.

How Colazide / Balsalazide Capsules Work

Colazide works by calming inflammation inside the bowel lining. In ulcerative colitis, the colon becomes swollen and irritated, leading to symptoms such as pain, diarrhoea, and bleeding. Balsalazide acts directly on the cells lining the intestine, changing how certain chemicals are produced. These chemicals are linked to inflammation and irritation. By reducing this response, the medicine:

  • Relaxes inflamed bowel tissue.
  • Reduces pain and discomfort.
  • Supports healing of damaged areas.
  • Lowers the risk of flare-ups returning.

This targeted approach makes it an effective option for ongoing bowel care and gut health maintenance.

What Conditions Do Colazide / Balsalazide Capsules Treat?

Colazide is mainly used for inflammatory bowel conditions rather than typical IBS alone. However, many people with IBS-like symptoms caused by inflammation benefit from this treatment. It is commonly prescribed for:

  • Ulcerative colitis relief.
  • Colon inflammation treatment.
  • Long-term digestive health management.
  • Bowel conditions involving irritation and ulceration.

It plays a key role in stabilising symptoms and maintaining remission.

How to Take Colazide / Balsalazide Capsules

Always follow your prescribed instructions carefully.

General guidance:

  • Swallow capsules whole with water.
  • Do not open or chew the capsules.
  • Take after meals or a light snack.
  • Take doses at evenly spaced times each day.

Typical dosage: Initial treatment: Often three capsules, three times daily. Maintenance phase: Reduced to two capsules, twice daily once symptoms improve.

Helpful tips: Take consistently for best results. Continue even if symptoms improve. Do not double doses if one is missed.

Regular use is essential for effective bowel inflammation treatment and long-term stability.

Who Can Use Colazide / Balsalazide Capsules?

Colazide capsules are typically suitable for adults managing inflammatory bowel conditions. They may be appropriate if you:

  • Experience symptoms linked to ulcerative colitis.
  • Need long-term bowel inflammation relief.
  • Are looking for prescription gut therapy.
  • Require maintenance treatment to prevent flare-ups.

Extra care may be required if you:

  • Have kidney or liver concerns.
  • Have asthma or allergies.
  • Are pregnant or breastfeeding.
  • Have reacted to aspirin or similar medicines before.

Possible Side Effects of Colazide / Balsalazide Capsules

Like all medicines, Colazide may cause side effects, although not everyone experiences them.

Common side effects:

  • Nausea or feeling sick.
  • Diarrhoea or stomach discomfort.
  • Headaches.
  • Joint or muscle aches.

Serious side effects (seek urgent attention):

  • Swelling of the face, lips, or throat.
  • Difficulty breathing.
  • Unusual bruising or bleeding.
  • Persistent fever or feeling unwell.

Most mild effects settle as your body adjusts to the treatment.

Interactions with Other Medicines

Colazide may interact with other treatments, which can affect how it works. Take care if using:

  • Other anti-inflammatory medicines.
  • Treatments affecting the immune system.
  • Over-the-counter or herbal supplements.

Always ensure your current treatments are reviewed before starting this medicine.

Supporting Your Gut Health During Treatment

While Colazide works on inflammation, small lifestyle steps can improve results.

  • Stay well hydrated.
  • Eat balanced, gentle meals.
  • Avoid known trigger foods.
  • Stick to your treatment routine.

Combining medication with simple habits supports better digestive health and long-term bowel care.

Why Do People Choose Colazide / Balsalazide Capsules?

People choose Colazide because it focuses on the underlying inflammation rather than just easing symptoms temporarily. Key reasons include:

  • Targets inflammation directly in the colon.
  • Supports long-term bowel stability.
  • Reduces flare-up frequency.
  • Suitable for ongoing prescription bowel therapy.
  • Helps restore comfort and daily routine.

For those dealing with recurring bowel issues, this treatment offers a more structured and reliable approach.

Mesalazine & Bowel Inflammation Treatments

These medicines are used to reduce inflammation in the bowel and are commonly prescribed for inflammatory bowel conditions such as ulcerative colitis. The table below compares commonly prescribed bowel inflammation treatments and how they are typically used.

ProductWhat it isWhat it's mainly used forHow you usually use itWhat to expect
Asacol / Mesalazine TabletsMesalazine anti-inflammatory tabletsUlcerative colitis and bowel inflammationTaken regularly as prescribedHelps reduce inflammation inside the bowel.
Mezavant / Mesalazine TabletsLong-acting mesalazine tabletsUlcerative colitisTaken once dailyDesigned for slow release throughout the bowel.
Octasa / Mesalazine TabletsMesalazine tabletsInflammatory bowel conditionsTaken regularlyHelps maintain symptom control and reduce flare-ups.
Pentasa / Mesalazine TabletsMesalazine tabletsBowel inflammationTaken regularlySlow-release treatment for ongoing inflammation control.
Pentasa / Mesalazine SachetsMesalazine granule sachetsUlcerative colitis and bowel inflammationTaken as prescribedSachet form may be easier for some people than tablets.
Salofalk / Mesalazine TabletsMesalazine tabletsInflammatory bowel diseaseTaken regularlyHelps manage bowel inflammation over time.
Salofalk / Mesalazine SachetsMesalazine granule sachetsBowel inflammationTaken as prescribedGranule form designed for bowel delivery.
Colazide / Balsalazide CapsulesAnti-inflammatory bowel capsulesUlcerative colitisTaken regularlyTargets inflammation in the large bowel.
OlsalazineAnti-inflammatory bowel medicineUlcerative colitisTaken regularlyHelps reduce bowel inflammation and maintain remission.
Sulfasalazine / Salazopyrin TabletsAnti-inflammatory bowel tabletsUlcerative colitis and inflammatory bowel conditionsTaken regularlyHelps control bowel inflammation and symptoms.

Important: This comparison is for general information only and does not replace medical advice. A prescriber will decide which treatment is suitable for you following an online consultation.

How to Order Colazide / Balsalazide Capsules Online from Pharmacy Planet

Ordering Colazide capsules is simple and secure.

  1. Complete the Online Consultation — Provide details about your symptoms and health.
  2. Prescription Review — A UK-registered prescriber confirms if Colazide is suitable.
  3. Discreet Delivery — If approved, your treatment is delivered directly to your chosen address.
Colazide/Balsalazide Capsules

Living with ongoing bowel discomfort, urgency, or frequent diarrhoea can quickly take over your day. Colazide / Balsalazide Capsules are designed for people dealing with inflammation in the bowel, offering targeted relief where it matters most.

This prescription bowel therapy works directly in the colon to reduce irritation, calm symptoms, and support long-term gut health. Unlike general digestive treatments, Colazide focuses on the root cause – inflammation in the lining of the bowel. This makes it a trusted option for ulcerative colitis relief and ongoing bowel care when symptoms keep returning.

Colazide capsules contain balsalazide, a type of anti-inflammatory gut medicine used to treat conditions affecting the large intestine. It belongs to a group of medicines commonly used in bowel inflammation treatment.

Once taken, balsalazide travels to the colon, where it releases its active component. This targeted action supports healing in the affected area without unnecessary impact on the rest of the body. This makes it suitable for:

  • Ulcerative colitis treatment.
  • Long-term colon inflammation treatment.
  • Managing recurring bowel symptoms.
  • Supporting digestive health in inflammatory conditions.

Colazide works by calming inflammation inside the bowel lining. In ulcerative colitis, the colon becomes swollen and irritated, leading to symptoms such as pain, diarrhoea, and bleeding. Balsalazide acts directly on the cells lining the intestine, changing how certain chemicals are produced. These chemicals are linked to inflammation and irritation. By reducing this response, the medicine:

  • Relaxes inflamed bowel tissue.
  • Reduces pain and discomfort.
  • Supports healing of damaged areas.
  • Lowers the risk of flare-ups returning.

This targeted approach makes it an effective option for ongoing bowel care and gut health maintenance.

Colazide is mainly used for inflammatory bowel conditions rather than typical IBS alone. However, many people with IBS-like symptoms caused by inflammation benefit from this treatment. It is commonly prescribed for:

  • Ulcerative colitis relief.
  • Colon inflammation treatment.
  • Long-term digestive health management.
  • Bowel conditions involving irritation and ulceration.

It plays a key role in stabilising symptoms and maintaining remission.

Always follow your prescribed instructions carefully.

General guidance:

  • Swallow capsules whole with water.
  • Do not open or chew the capsules.
  • Take after meals or a light snack.
  • Take doses at evenly spaced times each day.

Typical dosage: Initial treatment: Often three capsules, three times daily. Maintenance phase: Reduced to two capsules, twice daily once symptoms improve.

Helpful tips: Take consistently for best results. Continue even if symptoms improve. Do not double doses if one is missed.

Regular use is essential for effective bowel inflammation treatment and long-term stability.

Colazide capsules are typically suitable for adults managing inflammatory bowel conditions. They may be appropriate if you:

  • Experience symptoms linked to ulcerative colitis.
  • Need long-term bowel inflammation relief.
  • Are looking for prescription gut therapy.
  • Require maintenance treatment to prevent flare-ups.

Extra care may be required if you:

  • Have kidney or liver concerns.
  • Have asthma or allergies.
  • Are pregnant or breastfeeding.
  • Have reacted to aspirin or similar medicines before.

Like all medicines, Colazide may cause side effects, although not everyone experiences them.

Common side effects:

  • Nausea or feeling sick.
  • Diarrhoea or stomach discomfort.
  • Headaches.
  • Joint or muscle aches.

Serious side effects (seek urgent attention):

  • Swelling of the face, lips, or throat.
  • Difficulty breathing.
  • Unusual bruising or bleeding.
  • Persistent fever or feeling unwell.

Most mild effects settle as your body adjusts to the treatment.

Colazide may interact with other treatments, which can affect how it works. Take care if using:

  • Other anti-inflammatory medicines.
  • Treatments affecting the immune system.
  • Over-the-counter or herbal supplements.

Always ensure your current treatments are reviewed before starting this medicine.

While Colazide works on inflammation, small lifestyle steps can improve results.

  • Stay well hydrated.
  • Eat balanced, gentle meals.
  • Avoid known trigger foods.
  • Stick to your treatment routine.

Combining medication with simple habits supports better digestive health and long-term bowel care.

People choose Colazide because it focuses on the underlying inflammation rather than just easing symptoms temporarily. Key reasons include:

  • Targets inflammation directly in the colon.
  • Supports long-term bowel stability.
  • Reduces flare-up frequency.
  • Suitable for ongoing prescription bowel therapy.
  • Helps restore comfort and daily routine.

For those dealing with recurring bowel issues, this treatment offers a more structured and reliable approach.

Mesalazine & Bowel Inflammation Treatments

These medicines are used to reduce inflammation in the bowel and are commonly prescribed for inflammatory bowel conditions such as ulcerative colitis. The table below compares commonly prescribed bowel inflammation treatments and how they are typically used.

ProductWhat it isWhat it's mainly used forHow you usually use itWhat to expect
Asacol / Mesalazine TabletsMesalazine anti-inflammatory tabletsUlcerative colitis and bowel inflammationTaken regularly as prescribedHelps reduce inflammation inside the bowel.
Mezavant / Mesalazine TabletsLong-acting mesalazine tabletsUlcerative colitisTaken once dailyDesigned for slow release throughout the bowel.
Octasa / Mesalazine TabletsMesalazine tabletsInflammatory bowel conditionsTaken regularlyHelps maintain symptom control and reduce flare-ups.
Pentasa / Mesalazine TabletsMesalazine tabletsBowel inflammationTaken regularlySlow-release treatment for ongoing inflammation control.
Pentasa / Mesalazine SachetsMesalazine granule sachetsUlcerative colitis and bowel inflammationTaken as prescribedSachet form may be easier for some people than tablets.
Salofalk / Mesalazine TabletsMesalazine tabletsInflammatory bowel diseaseTaken regularlyHelps manage bowel inflammation over time.
Salofalk / Mesalazine SachetsMesalazine granule sachetsBowel inflammationTaken as prescribedGranule form designed for bowel delivery.
Colazide / Balsalazide CapsulesAnti-inflammatory bowel capsulesUlcerative colitisTaken regularlyTargets inflammation in the large bowel.
OlsalazineAnti-inflammatory bowel medicineUlcerative colitisTaken regularlyHelps reduce bowel inflammation and maintain remission.
Sulfasalazine / Salazopyrin TabletsAnti-inflammatory bowel tabletsUlcerative colitis and inflammatory bowel conditionsTaken regularlyHelps control bowel inflammation and symptoms.

Important: This comparison is for general information only and does not replace medical advice. A prescriber will decide which treatment is suitable for you following an online consultation.

Ordering Colazide capsules is simple and secure.

  1. Complete the Online Consultation — Provide details about your symptoms and health.
  2. Prescription Review — A UK-registered prescriber confirms if Colazide is suitable.
  3. Discreet Delivery — If approved, your treatment is delivered directly to your chosen address.
Frequently Asked Questions

Some symptom relief may begin within a few weeks, but full improvement in bowel inflammation and stability usually takes longer with consistent daily use.

Yes, by reducing inflammation in the colon, Colazide can gradually reduce diarrhoea and improve bowel control over time when taken regularly.

Yes, continuing treatment helps keep inflammation under control and reduces the chance of symptoms returning or flare-ups developing again.

It is usually taken after meals or snacks, which can reduce stomach upset and improve how well your body tolerates the medicine.

Take it when you remember unless your next dose is due soon. Skip the missed one if needed and continue as normal without doubling doses.

Some people notice mild stomach upset or diarrhoea initially, but this often settles as your body adjusts to the treatment.

Yes, it is often used long-term to maintain bowel stability and prevent inflammation from coming back once symptoms are under control.

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Review By

HARMINDER ‘HARMY’ KAUR

Last Updated On : Mar 13 2026

BSc(hons) Pharmacy

GPhC Number: 2061107

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GURDEV SEHMI

Last Reviewed On : Mar 23 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925