| |
| Active ingredient |
| How to take it |
| How it works |
| Effectiveness |
|
|
|
|
Tirzepatide (GLP-1 & GIP) |
|
Once weekly injection |
|
Acts on two pathways to reduce hunger and food cravings. |
|
|
|
|
|
|
Orforglipron (GLP-1) |
|
Once daily tablet, at any time, with or without food |
|
Acts on pathways to help you feel fuller and less hungry. |
|
About 7-11% at 72 weeks, depending on dosage. |
|
|
|
|
Semaglutide (GLP-1) |
|
Once weekly injection |
|
Helps you feel fuller and less hungry, reduces food cravings. |
|
About 15% at 68 weeks. |
|
|
|
|
Semaglutide (GLP-1) |
|
Once daily tablet after an 8 hour fast with up to 120ml of water; wait 30 minutes before food, drink or other tablets. |
|
Helps you feel fuller for longer, reduces food cravings. |
|
About 14% at 64 weeks. |
|
|
|
|
Liraglutide (GLP-1) |
|
Once daily injection |
|
Helps you feel fuller and less hungry. |
|
About 8% at 56 weeks. |
|
|
|
|
Orlistat |
|
One capsule with each main meal containing fat, up to 3 times daily. |
|
Reduces the amount of dietary fat absorbed by the body. |
|
About 5-10% over 12 months. |
|
|
|
|
Naltrexone & Bupropion |
|
Tablets increased gradually to 2 tablets twice daily. |
|
Acts on appetite and reward pathways to reduce hunger and cravings. |
|
About 5-9% at 56 weeks. |
|