Premarin Tablets
Premarin tablets are used as hormone replacement therapy (HRT). This medication manages symptoms of menopause. Premarin contains conjugated oestrogens, which emulate the female sex hormone oestrogen. During menopause, the production of oestrogen in a woman’s ovaries gradually stops. This deficiency can lead to a number of symptoms, including hot flushes, depression, sleep problems, vaginal dryness and osteoporosis. For severe symptoms, you may be prescribed Premarin to supplement the body’s oestrogen levels. It is available on prescription only in the UK and comes in multiple strengths – 0.3 mg, 0.625 mg, and 1.25 mg. You can buy Premarin tablets from Pharmacy Planet by completing the online consultation.
the items you wish
to order
by our qualified
prescriber
to your door step
Please use the options provided to make your final selection.

It is the prescribers duty to ensure that the medicine is being used safely and appropriately. please answer a few questions about yourself to help us process your request.
Customer Service Team
Confidentiality & Authenticity Assured
- Fully Regulated UK Pharmacy
- Authentic UK sourced medicines only.
- Trading for more than 10 years.
- Information Governance lead ensures all data is confidential
Need Help With Your Questionnaire?
Our customer service team is on hand Monday-Friday to help you with your queries.
Please call us on 08009788956 or
email us at: headoffice@pharmacyplanet.com
Select your preferred options and see the best price
| Pack | Price (£) | ||
|---|---|---|---|
| - | 0.3mg | 84 Tablets (3 months) | 44.00 |
| - | 1.25mg | 84 Tablets (3 months) | 74.00 |
| - | 0.625mg | 84 Tablets (3 months) | 48.00 |
| - | 0.3mg | 168 Tablets (6 Months) | 79.00 |
| - | 0.625mg | 168 Tablets (6 Months) | 86.00 |
| - | 1.25mg | 168 Tablets (6 Months) | 132.00 |
It looks like you missed filling in questions from the last consultation.Click Here to submit your response.
No subscriptions or hidden fees
Secure checkout

UK Regulated online pharmacy
Trusted by over 250,000+ happy customers
What is Premarin?
Premarin is a female hormone that is used for the treatment of symptoms related to menopause such as hot flashes and vaginal dryness. Apart from treating these symptoms, Premarin may be indicated in the treatment of osteoporosis in women after menopause. It is also used to treat cancers such as breast cancer or prostate cancer in women and men. It can also be used to replace oestrogen in women who cannot produce enough oestrogen due to hypogonadism.
How Does Premarin Work?
When women reach menopause, the ovaries produce less oestrogen, which causes the symptoms of menopause. The conjugated oestrogens in Premarin act as oestrogen replacement hormones that can manage menopausal symptoms such as spotting, chills, sweating and hot flashes. Oestrogen deficiency may also cause osteoporosis in women, which can be treated by Premarin as well.
What Are the Benefits of Taking Premarin?
Premarin is made up of conjugated oestrogens, which is a mixture of oestrogens also known as oestrogen replacement therapy. Oestrogen is a female sex hormone that is produced by the ovaries and used by many processes in the body.
Premarin has the following benefits:
- Manages symptoms of menopause
- Treats osteoporosis caused by oestrogen deficiency
- May treat certain types of cancer in men and women
- Replaces natural oestrogen when the body is not able to produce it due to any reason
How Do I Use Premarin
Premarin is an oral tablet that is to be taken by the mouth without chewing, crushing or dissolving the tablet. The medicine can be taken with or after a meal to reduce the chances of an upset stomach.
Premarin should be taken regularly as directed by your doctor for maximum benefit. Take it at the same time every day and follow the correct dosing schedule given by your doctor.
Premarin Dosage
Premarin may be taken daily or for certain conditions your doctor may prescribe Premarin in a cycle. The dosage should be kept according to your doctor’s prescription.
If you miss a dose, you can take it as soon as you remember it. However, if it is almost time for the next dose, you should skip it. Do not take a double dose to make up for the dose that you have missed.
Premarin Precautions and Side Effects
Side Effects
Premarin has certain side effects on some individuals. These side effects may not occur at all or may be non-serious in most cases.
Some common side effects of Premarin include:
- Nausea, stomach pain or gas
- Headache
- Back pain
- Depression
- Insomnia
- Breast pain; or
- Vaginal itching or discharge
- Changes in menstrual periods
- Breakthrough bleeding.
If these side effects persist or worsen, contact your doctor right away.
Premarin also has some other side effects that are rare but quite serious and may require immediate medical attention. These include:
- Heart attack symptoms
- Signs of a stroke
- Signs of a blood clot
- Swollen or tender stomach
- Jaundice
- Disorientation, memory problems, confusion
- Spotting or pelvic pain
- A lump in your breast
- High levels of calcium in your blood
Since every individual reacts to medicines differently, this is not a complete list of all possible side effects. If you notice other side effects not mentioned above, get medical attention and contact your pharmacist or physician for more information.
Warnings
Before taking Premarin, you should:
- Discuss your extensive medical history with your doctor especially if you belong to any of the high-risk groups mentioned below.
- Inform your doctor if you are pregnant, planning for a baby or currently breast-feeding an infant.
- Be informed that using this medicine may increase risk of blood clots, heart attacks and strokes especially if you have diabetes, high BP, high cholesterol or if you are overweight.
Precautions
While taking Premarin you should follow some precautions such as:
- Inform your doctor or dentist about your Premarin intake before a surgical procedure.
- Tell your doctor if you will be confined to a chair or bed for a long time as it may increase risks of blood clots while on this medicine.
- Avoid using tobacco or smoking as they can increase your risk of high BO, Heart attack, stroke or blood clots especially if you are older than 35.
- Wear protective clothes and sunscreen while in sun and limit your sun exposure as Premarin may cause melasma on your face of skin that is worsened by sun exposure.
- Tell your doctor if you become pregnant or want to breastfeed while on Premarin as it passes into breast milk and should not be taken by pregnant women.
- Premarin may cause vision problems in people who wear contact lenses, or are near sighted. Contact your doctor if you face any such problems.
- Avoid consuming grapefruit or grapefruit juice. Conjugated oestrogens may interact with grapefruit or grapefruit juice to show unwanted side effects.
High-Risk Groups
High-risk groups for Premarin include:
- People who have had a hysterectomy
- Individuals with heart disease
- People with liver problems, kidney diseases or gallbladder disease
- Asthma patients
- People with epilepsy or other seizure disorders
- Individuals who suffer from migraines
- People with Lupus
- Women with endometriosis or uterine fibroid tumours
- People with hereditary angioedema
- Individuals who suffer from porphyria
- People who have a thyroid disorder
- People with high levels of calcium in their blood.
Premarin Indications
Premarin is indicated in the treatment of:
- Abnormal Uterine Bleeding or spotting
- Atrophic Vaginitis
- Hypoestrogenism
- Osteoporosis
- Postmenopausal Symptoms
- Primary Ovarian Failure
- Prostate Cancer or breast cancer
How Do I Buy Premarin Online?
You can easily buy Premarin HRT tablets online by filling an online prescription form on [this website]. Premarin should be taken exactly as directed by your physician. Any misuse of the drug can have potentially harmful effects on your health. Contact your doctor for more information on the side effects and benefits of the medication.
Premarin is a female hormone that is used for the treatment of symptoms related to menopause such as hot flashes and vaginal dryness. Apart from treating these symptoms, Premarin may be indicated in the treatment of osteoporosis in women after menopause. It is also used to treat cancers such as breast cancer or prostate cancer in women and men. It can also be used to replace oestrogen in women who cannot produce enough oestrogen due to hypogonadism.
When women reach menopause, the ovaries produce less oestrogen, which causes the symptoms of menopause. The conjugated oestrogens in Premarin act as oestrogen replacement hormones that can manage menopausal symptoms such as spotting, chills, sweating and hot flashes. Oestrogen deficiency may also cause osteoporosis in women, which can be treated by Premarin as well.
Premarin is made up of conjugated oestrogens, which is a mixture of oestrogens also known as oestrogen replacement therapy. Oestrogen is a female sex hormone that is produced by the ovaries and used by many processes in the body.
Premarin has the following benefits:
- Manages symptoms of menopause
- Treats osteoporosis caused by oestrogen deficiency
- May treat certain types of cancer in men and women
- Replaces natural oestrogen when the body is not able to produce it due to any reason
Premarin is an oral tablet that is to be taken by the mouth without chewing, crushing or dissolving the tablet. The medicine can be taken with or after a meal to reduce the chances of an upset stomach.
Premarin should be taken regularly as directed by your doctor for maximum benefit. Take it at the same time every day and follow the correct dosing schedule given by your doctor.
Premarin may be taken daily or for certain conditions your doctor may prescribe Premarin in a cycle. The dosage should be kept according to your doctor’s prescription.
If you miss a dose, you can take it as soon as you remember it. However, if it is almost time for the next dose, you should skip it. Do not take a double dose to make up for the dose that you have missed.
Side Effects
Premarin has certain side effects on some individuals. These side effects may not occur at all or may be non-serious in most cases.
Some common side effects of Premarin include:
- Nausea, stomach pain or gas
- Headache
- Back pain
- Depression
- Insomnia
- Breast pain; or
- Vaginal itching or discharge
- Changes in menstrual periods
- Breakthrough bleeding.
If these side effects persist or worsen, contact your doctor right away.
Premarin also has some other side effects that are rare but quite serious and may require immediate medical attention. These include:
- Heart attack symptoms
- Signs of a stroke
- Signs of a blood clot
- Swollen or tender stomach
- Jaundice
- Disorientation, memory problems, confusion
- Spotting or pelvic pain
- A lump in your breast
- High levels of calcium in your blood
Since every individual reacts to medicines differently, this is not a complete list of all possible side effects. If you notice other side effects not mentioned above, get medical attention and contact your pharmacist or physician for more information.
Warnings
Before taking Premarin, you should:
- Discuss your extensive medical history with your doctor especially if you belong to any of the high-risk groups mentioned below.
- Inform your doctor if you are pregnant, planning for a baby or currently breast-feeding an infant.
- Be informed that using this medicine may increase risk of blood clots, heart attacks and strokes especially if you have diabetes, high BP, high cholesterol or if you are overweight.
Precautions
While taking Premarin you should follow some precautions such as:
- Inform your doctor or dentist about your Premarin intake before a surgical procedure.
- Tell your doctor if you will be confined to a chair or bed for a long time as it may increase risks of blood clots while on this medicine.
- Avoid using tobacco or smoking as they can increase your risk of high BO, Heart attack, stroke or blood clots especially if you are older than 35.
- Wear protective clothes and sunscreen while in sun and limit your sun exposure as Premarin may cause melasma on your face of skin that is worsened by sun exposure.
- Tell your doctor if you become pregnant or want to breastfeed while on Premarin as it passes into breast milk and should not be taken by pregnant women.
- Premarin may cause vision problems in people who wear contact lenses, or are near sighted. Contact your doctor if you face any such problems.
- Avoid consuming grapefruit or grapefruit juice. Conjugated oestrogens may interact with grapefruit or grapefruit juice to show unwanted side effects.
High-Risk Groups
High-risk groups for Premarin include:
- People who have had a hysterectomy
- Individuals with heart disease
- People with liver problems, kidney diseases or gallbladder disease
- Asthma patients
- People with epilepsy or other seizure disorders
- Individuals who suffer from migraines
- People with Lupus
- Women with endometriosis or uterine fibroid tumours
- People with hereditary angioedema
- Individuals who suffer from porphyria
- People who have a thyroid disorder
- People with high levels of calcium in their blood.
Premarin is indicated in the treatment of:
- Abnormal Uterine Bleeding or spotting
- Atrophic Vaginitis
- Hypoestrogenism
- Osteoporosis
- Postmenopausal Symptoms
- Primary Ovarian Failure
- Prostate Cancer or breast cancer
You can easily buy Premarin HRT tablets online by filling an online prescription form on [this website]. Premarin should be taken exactly as directed by your physician. Any misuse of the drug can have potentially harmful effects on your health. Contact your doctor for more information on the side effects and benefits of the medication.
If you take more than the prescribed dose, you may experience symptoms such as nausea, vomiting, breast tenderness, stomach pain, fatigue or tiredness. An overdose of oestrogen may lead to withdrawal bleeding in women. Treatment for overdose includes stopping Premarin and providing appropriate symptomatic care.
You can use Premarin cream on your face for up to two years, and it may result in an increase in skin thickness and a reduction in wrinkles.
Premarin contains oestrogen, which can increase the chances of developing breast or uterine cancer. If you have, have had, or have a family history of such cancers, consult your healthcare professional before using this medication to understand the potential health risks involved.
It is advisable to avoid smoking while taking medications containing oestrogen. Cigarette smoking increases the risk of cardiovascular issues such as heart attack, stroke, deep vein thrombosis, and pulmonary embolism.
Premarin may increase the chances of blood clots, strokes, or heart attacks. So, it is essential to consult a healthcare provider before starting this medication.
Long-term use of this medicine may increase the risk of dementia, particularly in women over 65 years of age.
clinical consultation
Answer a few questions on your health and your fitness goals.
assessment
Our clinicians will review your clinical questionnaire to make sure treatment is right for you.
aboard!
Once approved, you will access our wealth of experience and resources curated by our team and begin your clinical journey.
Start your journey with us
Need Help?

Start your weight loss journey heading in the right direction. Our team are here to help. Whether you’re unsure about which medicine is right for you or need help navigating the world of weight loss drugs, our team are on hand to help you make the right decision. We can put you in touch with one of our experienced weight loss clinicians so you can be sure you’re making the best decision with the most accurate information.
To get in touch, contact our Customer Service team on 0800 978 8956 or email headoffice@pharmacyplanet.com.
Review By
GURDEV SEHMI
Last Updated On : Mar 13 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925
Authored By
GURDEV SEHMI
Last Reviewed On : Mar 23 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925


