Premique Low Dose
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Select your preferred options and see the best price
| Pack | Price (£) | ||
|---|---|---|---|
| Premique Low Dose | - | 168 Tablets (6 Months) | 101.00 |
| Premique Low Dose | - | 84 Tablets (3 months) | 53.00 |
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What is Premique?
Premique is a hormonal drug. The drug is used as part of hormonal therapies in women. The active ingredients in Premique are estradiol (an estrogen hormone) and medroxyprogesterone (a progestin hormone). Lack of estrogen arises when, in the course of menopause, the ovaries produce fewer and fewer estrogen hormones. As a result, uncomfortable complaints often occur. Premique refreshes the hormonal balance, making the symptoms decrease or disappear completely. This medication is only available by prescription.
How does it work?
As menopause occurs, women begin to produce less estrogen, resulting in a decrease in estrogen levels in the blood. As a result, the decrease in estrogen levels produces several uncomfortable symptoms. Premique is a period less therapy, which means that you will not experience monthly bleeding with this treatment.
The benefits of Premique are thanks to the components it contains, two active ingredients, conjugated estrogens, which complement the lack of estrogens, helping to reduce the symptoms of menopause. The second principle is medroxyprogesterone acetate. For women who have not had a hysterectomy, increased estrogen levels can stimulate the growth of the uterine lining, which can cause uterine cancer. The inclusion of progesterone is done to counteract the effects of estrogen on the uterine lining, which reduces the risk of cancer.
What are the benefits of taking it?
Premique tablets for Hormone Replacement Therapy (HRT for women), it is a continuous combination of treatments, and are used to alleviate menopausal symptoms. They contain synthetic versions of estrogens and progesterone, which help restore naturally lowered hormone levels. Premique is prescribed, among other things, for the treatment of the following menopausal symptoms:
- Hot flushes
- An increased level of sweat (night)
- Bone loss
- Sleep disorders
- Dry mucous membranes (in eyes and vagina)
- Humor changes.
The progestin hormone contained in Premique (Climopax) protects the uterus from side effects. Therefore, this drug is mainly prescribed to women whose uterus has not been removed.
How do I use it?
The tablets should be taken with a little water at a fixed time. This can be done before, during, or after meals. The tablets are arranged on a blister strip with dates. If a blister strip is used, continue with a new blister strip. There is no 7-day break when using Premique. There is also no bleeding when using Premique. Do not use Premique for more than two years in a row without first consulting your doctor.
Its dosage
Premique is generally prescribed in the lowest dose for the shortest period of time, in a 28-day package. For both Premique dosages, it is recommended to take one tablet at the same time every day, with no breaks between packages. If you are not currently taking another HRT or HRT with no period, you can start the first Premique pack at any time. If you are using a treatment that allows you to have periods, it is generally recommended that you start this HRT after the cycle of your previous therapy ends.
It is important that you take this medicine as prescribed by your doctor. If you forget to take a pill, you should take it as soon as possible. However, if more than 12 hours pass, it is recommended to skip the dose and continue treatment at the usual time. Do not double the dose to make up for the forgotten pill.
Side effects & precautions
It is essential to be aware of the side effects that this product can induce, since some may require that you go to the doctor urgently. Visit your nearest doctor or hospital right away if you notice any signs that may be an indication of the following: a heart attack or stroke; an allergic reaction; liver disease; migraine for the first time or one that is worse than normal; breast cancer or any type of cancer that is sensitive to estrogens; a blood clot; or increased blood pressure.
Very common (1 in 10 women or more):
Chest pain.
Common (1 in 10 women or less):
The appearance of bleeding or spotting, inflammation of the vagina, menstrual pain, tender or swollen breasts, nipple discharge, depression, muscle and joint pain, leg cramps, weight fluctuations, or altered triglyceride levels.
Uncommon (1 in 100 women or less):
Oral thrush, irregular menstrual bleeding, vaginal discharge, feeling unwell, bloating, abdominal pain, headache, blood clot in a vein, migraine, dizziness, mood changes, libido changes, swelling of the face or ankles, itching, acne, intolerance to contact lenses, gallbladder disease, or hair loss.
Rare (1 in 1,000 women or less):
Irritability, vomiting, changes in breast tissue, increased hair growth, worsening of asthma symptoms, increase in fibroid size, ovarian cancer, worsening of epilepsy, myocardial infarction, stroke, or inflammation of the pancreas.
Precautions and Warnings
This treatment is not suitable for those who have a history of the following diseases: heart conditions such as angina; heart attack or stroke; blood clots, or any disorder that affects blood clotting; breast cancer, or any type of cancer that responds to estrogens; porphyria; lactose or sucrose intolerance; recent excessive vaginal bleeding; endometrial hyperplasia; or severe liver disease.
People with the following conditions are also recommended to take special care or have regular check-ups when using this medicine: endometriosis; uterine fibers; increased susceptibility to blood clots; any high-risk factors related to breast cancer or another form of estrogen-dependent cancer; high blood pressure; liver or kidney dysfunction; diabetes; gallbladder disease; migraine; systemic lupus erythematosus; epilepsy; hypocalcemia; hypertriglyceridaemia; asthma; or otosclerosis.
Buying Premique online
You can buy Premique Tablets online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy HR therapy medicine online, use Pharmacy Planet, a UK pharmacy you can trust.
What is the difference between Premique and Prempro?
Both Premique and Prempro contain the same active ingredients and are manufactured by Wyeth. The key difference between the medications lies in the levels of MPA. Premique contains 5.0mg of MPA, whereas Prempro contains 2.5mg of MPA.
Premique is a hormonal drug. The drug is used as part of hormonal therapies in women. The active ingredients in Premique are estradiol (an estrogen hormone) and medroxyprogesterone (a progestin hormone). Lack of estrogen arises when, in the course of menopause, the ovaries produce fewer and fewer estrogen hormones. As a result, uncomfortable complaints often occur. Premique refreshes the hormonal balance, making the symptoms decrease or disappear completely. This medication is only available by prescription.
As menopause occurs, women begin to produce less estrogen, resulting in a decrease in estrogen levels in the blood. As a result, the decrease in estrogen levels produces several uncomfortable symptoms. Premique is a period less therapy, which means that you will not experience monthly bleeding with this treatment.
The benefits of Premique are thanks to the components it contains, two active ingredients, conjugated estrogens, which complement the lack of estrogens, helping to reduce the symptoms of menopause. The second principle is medroxyprogesterone acetate. For women who have not had a hysterectomy, increased estrogen levels can stimulate the growth of the uterine lining, which can cause uterine cancer. The inclusion of progesterone is done to counteract the effects of estrogen on the uterine lining, which reduces the risk of cancer.
Premique tablets for Hormone Replacement Therapy (HRT for women), it is a continuous combination of treatments, and are used to alleviate menopausal symptoms. They contain synthetic versions of estrogens and progesterone, which help restore naturally lowered hormone levels. Premique is prescribed, among other things, for the treatment of the following menopausal symptoms:
- Hot flushes
- An increased level of sweat (night)
- Bone loss
- Sleep disorders
- Dry mucous membranes (in eyes and vagina)
- Humor changes.
The progestin hormone contained in Premique (Climopax) protects the uterus from side effects. Therefore, this drug is mainly prescribed to women whose uterus has not been removed.
The tablets should be taken with a little water at a fixed time. This can be done before, during, or after meals. The tablets are arranged on a blister strip with dates. If a blister strip is used, continue with a new blister strip. There is no 7-day break when using Premique. There is also no bleeding when using Premique. Do not use Premique for more than two years in a row without first consulting your doctor.
Premique is generally prescribed in the lowest dose for the shortest period of time, in a 28-day package. For both Premique dosages, it is recommended to take one tablet at the same time every day, with no breaks between packages. If you are not currently taking another HRT or HRT with no period, you can start the first Premique pack at any time. If you are using a treatment that allows you to have periods, it is generally recommended that you start this HRT after the cycle of your previous therapy ends.
It is important that you take this medicine as prescribed by your doctor. If you forget to take a pill, you should take it as soon as possible. However, if more than 12 hours pass, it is recommended to skip the dose and continue treatment at the usual time. Do not double the dose to make up for the forgotten pill.
It is essential to be aware of the side effects that this product can induce, since some may require that you go to the doctor urgently. Visit your nearest doctor or hospital right away if you notice any signs that may be an indication of the following: a heart attack or stroke; an allergic reaction; liver disease; migraine for the first time or one that is worse than normal; breast cancer or any type of cancer that is sensitive to estrogens; a blood clot; or increased blood pressure.
Very common (1 in 10 women or more):
Chest pain.
Common (1 in 10 women or less):
The appearance of bleeding or spotting, inflammation of the vagina, menstrual pain, tender or swollen breasts, nipple discharge, depression, muscle and joint pain, leg cramps, weight fluctuations, or altered triglyceride levels.
Uncommon (1 in 100 women or less):
Oral thrush, irregular menstrual bleeding, vaginal discharge, feeling unwell, bloating, abdominal pain, headache, blood clot in a vein, migraine, dizziness, mood changes, libido changes, swelling of the face or ankles, itching, acne, intolerance to contact lenses, gallbladder disease, or hair loss.
Rare (1 in 1,000 women or less):
Irritability, vomiting, changes in breast tissue, increased hair growth, worsening of asthma symptoms, increase in fibroid size, ovarian cancer, worsening of epilepsy, myocardial infarction, stroke, or inflammation of the pancreas.
Precautions and Warnings
This treatment is not suitable for those who have a history of the following diseases: heart conditions such as angina; heart attack or stroke; blood clots, or any disorder that affects blood clotting; breast cancer, or any type of cancer that responds to estrogens; porphyria; lactose or sucrose intolerance; recent excessive vaginal bleeding; endometrial hyperplasia; or severe liver disease.
People with the following conditions are also recommended to take special care or have regular check-ups when using this medicine: endometriosis; uterine fibers; increased susceptibility to blood clots; any high-risk factors related to breast cancer or another form of estrogen-dependent cancer; high blood pressure; liver or kidney dysfunction; diabetes; gallbladder disease; migraine; systemic lupus erythematosus; epilepsy; hypocalcemia; hypertriglyceridaemia; asthma; or otosclerosis.
You can buy Premique Tablets online through one of the UK’s leading online pharmacies, Pharmacy Planet. It's easy and convenient. You will need to fill out a short assessment and the item will be delivered directly to your door. If you want to buy HR therapy medicine online, use Pharmacy Planet, a UK pharmacy you can trust.
Both Premique and Prempro contain the same active ingredients and are manufactured by Wyeth. The key difference between the medications lies in the levels of MPA. Premique contains 5.0mg of MPA, whereas Prempro contains 2.5mg of MPA.
Yes, Premique is available on the NHS, but it may take some time to get a GP appointment. You can order Premique online easily from Pharmacy Planet following an online consultation and have it delivered to your doorstep promptly.
Premique contains conjugated oestrogen, i.e., different types of oestrogen, but Indivina contains estradiol. Both are used for treating menopausal symptoms in women.
The ingredients present in the medication are listed below: Active ingredients: Conjugated oestrogens & medroxyprogesterone acetate. Inactive ingredients:
- Lactose monohydrate
- Sucrose
- Calcium phosphate tribasic
- Calcium sulfate anhydrous
- Microcrystalline cellulose
- Carnauba wax
- Glyceryl mono-oleates
- Magnesium stearate
- Methylcellulose
- Macrogol
- Pharmaceutical glaze
- Povidone
- Titanium dioxide (E171)
- Stearic acid
- Iron oxide black (E172) shellac
- n-Butyl alcohol
- Propylene glycol
- Ethyl acetate
Premique starts working within a few weeks of starting the medication, and the full benefit may take up to three months. If you do not notice any improvement after three months, contact your healthcare professional, who may prescribe a higher dosage or recommend a similar medication to relieve the symptoms.
In rare cases, anxiety may occur as a side effect of using Premique. If this side effect persists for an extended period, contact your healthcare provider immediately.
You should read the patient information leaflet carefully before starting the medication to ensure its safe and effective use.
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Review By
GURDEV SEHMI
Last Updated On : Mar 13 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925
Authored By
GURDEV SEHMI
Last Reviewed On : Mar 23 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925


