Femodene ED Tablets
Femodene ED is an oral contraceptive. When used correctly, it will provide near 100% protection against pregnancy. Its two active ingredients, gestodene and ethinyl estradiol, prevent ovulation from occurring during the menstrual cycle. Femodene ED is a monophasic combined pill, meaning each pill contains the same dose of gestodene and ethinylestradiol. Femodene ED is available in a 28-day ED pill; your doctor will decide which is best for you and you should stick to this.
f you have been prescribed Femodene ED, repeat supplies can be purchased online from Pharmacy Planet following a simple medical questionnaire.
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| Pack | Price (£) | ||
|---|---|---|---|
| - | - | 84 Tablets (3 months) | 31.00 |
| - | - | 168 Tablets (6 Months) | 39.00 |
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Femodene ED Tablets | Combined Oral Contraceptive Pill for Pregnancy Prevention
Consistent Habit, Continuous Protection
Breaking the daily routine of tablet-taking during a pill-free week might seem like a minor inconvenience, but for some women it is a genuine source of confusion, missed pills, and anxiety about whether they are still protected. Femodene ED addresses this with a straightforward solution: a 28-day pack that contains both active and inactive tablets, so you take a pill every single day without interruption. Femodene ED is a combined oral contraceptive pill licensed in the United Kingdom for the prevention of pregnancy. It contains ethinylestradiol and gestodene, and is designed to be taken as a continuous 28-day cycle with no breaks. This page explains how it works, how to take it correctly, who it is and is not suitable for, and how to access it through a clinical consultation at Pharmacy Planet.
The ED in the name stands for every day. Unlike standard combined pills that involve 21 active tablets followed by a seven-day gap, Femodene ED contains 21 active tablets and seven inactive placebo tablets. You take all 28 in sequence, then start the next pack immediately. Some women find this format helps them stay on a consistent daily schedule, reducing the risk of restarting a new pack late.
What Is Femodene ED?
Femodene ED is a combined oral contraceptive tablet manufactured by Bayer plc. Each active tablet contains ethinylestradiol 30 micrograms and gestodene 75 micrograms. Ethinylestradiol is a synthetic oestrogen. Gestodene is a synthetic progestogen belonging to the third-generation class of progestogens. The seven inactive tablets in each pack contain no hormones and are included solely to maintain the unbroken daily pill-taking habit.
Femodene ED is a monophasic pill, meaning every active tablet in the pack contains exactly the same dose of both hormones throughout the 28-day cycle. This makes the regimen straightforward: the same tablet every day, with no need to track where you are in a variable-dose schedule.
Femodene ED is a Prescription Only Medicine. It cannot be purchased without a valid prescription from a registered clinician. Before any prescription is issued, a clinical consultation is required to confirm that a combined oestrogen-progestogen pill is appropriate for your health circumstances and to identify any contraindications or risk factors.
How Does Femodene ED Work?
Suppressing Ovulation
The primary contraceptive mechanism of Femodene ED is the suppression of ovulation. Ethinylestradiol and gestodene act together on the pituitary gland to inhibit the release of follicle-stimulating hormone and luteinising hormone. Without the luteinising hormone surge that normally triggers egg release, ovulation does not occur. This is the same primary mechanism shared by all combined oral contraceptives.
Secondary Mechanisms
Femodene ED also works through two secondary mechanisms that contribute to its contraceptive effect:
- Gestodene thickens the cervical mucus, making it more difficult for sperm to travel through the cervix.
- The hormonal combination alters the endometrium (the lining of the uterus), reducing its receptiveness to implantation even in the unlikely event that an egg were fertilised.
The Every Day Format
The seven inactive tablets in each Femodene ED pack serve no pharmacological purpose. They are placebo tablets designed to maintain an unbroken daily tablet-taking habit. A withdrawal bleed typically occurs during the seven inactive tablet days due to the drop in hormone levels. This bleed is not a true menstrual period but is a predictable consequence of the brief hormone-free interval.
Cycle Regulation
As a combined hormonal contraceptive, Femodene ED regulates the hormonal signals that govern the menstrual cycle. Many women find that their withdrawal bleeds become lighter and more predictable whilst taking a combined pill. Lighter periods are a recognised secondary effect of combined hormonal contraception and are not a cause for concern.
How to Take Femodene ED
Starting Your First Pack
Your prescriber will advise on the most appropriate starting day. The standard guidance is:
- Day 1 start: Begin on the first day of your period with the first active tablet. You are protected from pregnancy immediately.
- Day 2 to 5 start: Begin within the first five days of your cycle. Use additional contraception such as condoms for the first seven days.
- Switching from another combined pill: Take the first active Femodene ED tablet the day after your last active tablet from the previous pack. You remain protected immediately. Start from the beginning of the Femodene ED strip.
- Switching from a progestogen-only pill: You can switch on any day. Use additional contraception for the first seven days.
Taking the 28-Day Pack
Take one tablet every day at the same time, working through the pack in the printed sequence. After completing all 28 tablets, begin the next pack immediately the following day. There is no gap between packs.
- Swallow each tablet whole with water.
- Take tablets at the same time each day to maintain consistent hormone levels.
- Take tablets in the correct order as printed on the pack. Active and inactive tablets look different; do not confuse them.
- A withdrawal bleed will usually occur during the seven inactive tablet days. Continue taking tablets every day during this time.
If You Miss a Tablet
The rules differ depending on whether the tablet missed was an active or inactive tablet:
- Missed inactive tablet: no effect on contraceptive protection. Discard the missed inactive tablet and continue with the next tablet as normal.
- Missed one active tablet, fewer than 24 hours late: take the missed tablet immediately and continue as normal. You remain protected.
- Missed one active tablet, more than 24 hours late: take the missed tablet immediately and take the next one at the usual time, even if that means two in one day. Use additional contraception for seven days.
- Missed two or more active tablets: take the most recently missed tablet immediately. Leave other missed tablets. Continue the pack and use additional contraception for seven days. If you missed active tablets in the first week and had unprotected sex, contact your prescriber or pharmacist about emergency contraception.
If vomiting occurs within two hours of taking an active tablet, or if you have severe diarrhoea, treat the situation as a missed pill. Refer to the Patient Information Leaflet for complete missed pill guidance in all specific scenarios.
Dosage and Strengths Available
Tablet Composition
- Active tablets (21 per pack): ethinylestradiol 30 micrograms and gestodene 75 micrograms
- Inactive tablets (7 per pack): no active ingredients
- Monophasic formulation: every active tablet contains the same dose
Pack Format
- Each pack: 28 tablets (21 active and 7 inactive)
- Taken continuously, every day, with no break between packs
Dosage Regimen
One tablet daily at the same time for 28 consecutive days, then begin the next pack immediately. The dose is fixed: 30 micrograms of ethinylestradiol and 75 micrograms of gestodene in each active tablet. There is no titration or dose variation. Your prescriber will confirm the most appropriate starting day for your individual circumstances.
Side Effects and Safety Information
As with all medicines, Femodene ED can cause side effects. Not every woman will experience them. The following is a summary based on the current UK SmPC. Read the Patient Information Leaflet supplied with your medication in full before starting treatment.
Common Side Effects
- Headache or migraine
- Nausea
- Breast tenderness or pain
- Mood changes, including low mood or irritability
- Changes in libido
- Irregular spotting or breakthrough bleeding, especially in the first few cycles
- Changes in vaginal discharge
Less Common Side Effects
- Weight changes
- Changes in contact lens tolerance due to corneal effects
- Skin changes including chloasma (patches of darker skin on the face)
Serious Side Effects: Seek Urgent Medical Attention If You Experience
- Sudden chest pain, shortness of breath, or coughing up blood. These may indicate a pulmonary embolism or heart attack.
- Pain, swelling, or warmth in one leg. This may indicate deep vein thrombosis.
- Sudden severe headache, visual disturbance, weakness in the face, arm, or leg, or difficulty speaking. These may indicate a stroke.
- Severe abdominal pain, which may indicate a liver problem or ectopic pregnancy.
- Jaundice (yellowing of the skin or eyes).
Blood Clot Risk
All combined oral contraceptives carry a small increased risk of venous thromboembolism compared with women not using hormonal contraception. Gestodene-containing pills including Femodene ED are considered to carry a broadly similar VTE risk to desogestrel and drospirenone-containing combined pills, and a somewhat higher risk than levonorgestrel-containing pills. Your prescriber will assess your individual risk factors before prescribing, including BMI, smoking status, personal and family history of blood clots, and any planned periods of immobility.
Important Drug Interactions
Enzyme-inducing medicines can reduce the effectiveness of Femodene ED. These include:
- Rifampicin and rifabutin
- Certain antiepileptic medicines including phenytoin, carbamazepine, phenobarbital, and topiramate
- Some HIV medicines including ritonavir and efavirenz
- St John's Wort
Always disclose your full medication list, including herbal remedies and supplements, at every consultation. If you are prescribed an enzyme-inducing medicine whilst taking Femodene ED, additional contraceptive precautions or an alternative method may be required.
Who Can Take Femodene ED?
Femodene ED Is Not Suitable If You:
- Have or have ever had a blood clot (deep vein thrombosis, pulmonary embolism, or arterial thrombosis)
- Have or have ever had a stroke or heart attack
- Have migraine with aura
- Have uncontrolled high blood pressure
- Have liver disease or liver tumours
- Have or have ever had breast cancer or another oestrogen-sensitive cancer
- Are pregnant or think you may be pregnant
- Are breastfeeding a baby under six weeks old
- Are a smoker aged 35 or over
- Have diabetes with vascular complications
This Medicine May Be Appropriate If You:
- Are a healthy adult woman seeking reliable daily hormonal contraception
- Find maintaining a daily pill-taking habit easier without a seven-day break in your routine
- Have no personal or family history of blood clots, stroke, or cardiovascular disease
- Do not have migraine with aura and do not smoke heavily
- Are not currently taking medicines that interact significantly with combined oral contraceptives
Use With Caution If You:
- Are a smoker under the age of 35. Smoking increases cardiovascular risk with all oestrogen-containing contraceptives.
- Have a BMI above 30. Obesity is an independent risk factor for VTE.
- Have a family history of blood clots in a first degree relative under the age of 50.
- Have a history of depression. Combined hormonal contraceptives can affect mood in some women.
- Are planning long-haul travel or extended periods of immobility, which independently increase VTE risk.
- Have had high blood pressure during pregnancy or other oestrogen-sensitive conditions in the past.
Consultation and Prescribing Process
Pharmacy Planet is a GPhC registered UK online pharmacy. All prescriptions for Femodene ED are issued following a genuine clinical consultation conducted by a registered prescriber. The process works as follows:
- Complete a structured medical questionnaire covering your health history, current medicines, smoking status, BMI, family history of blood clots and cardiovascular disease, and any relevant gynaecological history. Accurate and complete answers are essential.
- A registered prescriber reviews your consultation individually and assesses whether Femodene ED is clinically appropriate for your specific circumstances, including the gestodene-related VTE risk profile.
- A prescription is issued only if the prescriber determines that Femodene ED is appropriate for you. Completing a consultation does not guarantee a prescription. The prescriber may determine that a different contraceptive is more suitable, or that further information or a face-to-face assessment is required.
- If a prescription is issued, your medication is dispensed and dispatched by our pharmacy team. Our team is available for any follow-up questions during or after treatment.
- Repeat supply requires a new consultation to confirm that continued prescribing remains appropriate for your current health.
Storage and Handling
- Store below 25°C.
- Keep tablets in the original blister pack to protect from moisture.
- Keep this medicine out of the sight and reach of children.
- Do not use tablets after the expiry date printed on the pack.
- Return unused tablets to your pharmacist for safe disposal. Do not dispose of medicines via wastewater or household waste.
Contraceptive Product Comparison | Pharmacy Planet
This reference guide compares the contraceptive preparations available at Pharmacy Planet, grouped by delivery method and formulation type. Every preparation is a Prescription Only Medicine. A registered prescriber will review your individual health profile, contraceptive history, and risk factors before recommending any preparation. This table is a clinical reference, not a recommendation.
Combined Oral Contraceptive Tablets (Monophasic)
Monophasic combined pills contain the same dose of both hormones in every active tablet. The table below compares commonly prescribed monophasic combined oral contraceptives by progestogen type, oestrogen dose, VTE risk category, pack format, and key clinical characteristics.
| Name | Progestogen | Estrogen | Classification | Dosage Regimen | Description |
|---|---|---|---|---|---|
| Rigevidon | Levonorgestrel 150 mcg | 30 mcg | Lowest | 21+7 | Generic of Microgynon 30 (Consilient Health) |
| Microgynon 30 | Levonorgestrel 150 mcg | 30 mcg | Lowest | 21+7 | Branded originator (Bayer); four-way equivalent family |
| Levest | Levonorgestrel 150 mcg | 30 mcg | Lowest | 21+7 | Generic (Morningside); clinically identical to above |
| Ovranette | Levonorgestrel 150 mcg | 30 mcg | Lowest | 21+7 | Generic (Pfizer); clinically identical to above |
| Microgynon 30 ED | Levonorgestrel 150 mcg | 30 mcg | Lowest | 28 ED | Every-day format; 21 active + 7 placebo tablets |
| Femodene | Gestodene 75 mcg | 30 mcg | Higher | 21+7 | 3rd-gen progestogen; branded originator (Bayer) |
| Femodene ED | Gestodene 75 mcg | 30 mcg | Higher | 28 ED | Every-day format of Femodene; 21 active + 7 placebo |
| Femodette | Gestodene 75 mcg | 20 mcg | Higher | 21+7 | Lower oestrogen version of Femodene |
| Millinette | Gestodene 75 mcg | 30 mcg/20 mcg | Higher | 21+7 | Generic of Femodene (Gedeon Richter) |
| Marvelon | Desogestrel 150 mcg | 30 mcg | Higher | 21+7 | 3rd-gen; branded originator (Organon) |
| Mercilon | Desogestrel 150 mcg | 20 mcg | Higher | 21+7 | Lower oestrogen version of Marvelon |
| Gedarel 30/150 | Desogestrel 150 mcg | 30 mcg | Higher | 21+7 | Generic of Marvelon (Consilient Health) |
| Gedarel 20/150 | Desogestrel 150 mcg | 20 mcg | Higher | 21+7 | Generic of Mercilon (Consilient Health) |
| Lizinna | Norgestimate 250 mcg | 35 mcg | Higher | 21+7 | Generic of discontinued Cilest; prodrug → norelgestromin |
| Cilique | Norgestimate 250 mcg | 35 mcg | Higher | 21+7 | Generic of discontinued Cilest (Consilient Health) |
| Yasmin | Drospirenone 3 mg | 30 mcg | Higher | 28 ED | Branded originator (Bayer); anti-mineralocorticoid activity; potassium interaction – check renal function |
| Lucette | Drospirenone 3 mg | 30 mcg | Higher | 28 ED | Generic of Yasmin (Stragen UK); same potassium interaction |
| Yacella | Drospirenone 3 mg | 30 mcg | Higher | 28 ED | Generic of Yasmin (Stragen UK); same potassium interaction |
| Eloine | Drospirenone 3 mg | 20 mcg | Higher | 28 ED (24+4) | Lower oestrogen; 24 active + 4 inactive; potassium interaction |
| Brevinor | Norethisterone 500 mcg | 35 mcg | Low | 21+7 | 1st-gen progestogen; mild androgenic activity |
| Norimin | Norethisterone 1 mg | 35 mcg | Low | 21+7 | Double norethisterone dose vs Brevinor; same oestrogen |
| Norinyl-1 | Norethisterone 1 mg | Mestranol 50 mcg | Low | 21+7 | Uses mestranol (prodrug) not EE directly; higher oestrogenic exposure than Norimin |
| Dianette (co-cyprindiol) | Cyproterone acetate 2 mg | 35 mcg | Higher | 21+7 | Anti-androgen; licensed for acne and hirsutism; not first-line contraceptive |
| Zoely | Nomegestrol acetate 2.5 mg | Estradiol 1.5 mg | Data limited | 28 ED (24+4) | Natural oestrogen (hemihydrate); 12-hour missed pill window; no generic |
Important: This comparison is for general information only and does not replace medical advice. A prescriber will decide which treatment is suitable for you following an online consultation.
Why Choose Pharmacy Planet?
Pharmacy Planet is a registered UK online pharmacy regulated by the General Pharmaceutical Council. We provide a clinically responsible and confidential route to accessing prescription contraception, including everyday combined pills such as Femodene ED. Our platform supports informed decision-making, with genuine clinical assessment at every stage.
Every prescriber working through our platform reviews consultations individually. They make clinical decisions based on your specific health profile, and if Femodene ED is not appropriate for you, they will tell you clearly. Our team will support you in exploring alternatives wherever that is possible. Clinical integrity is a feature of our service, not an inconvenience.
Our GPhC registration and the EU common logo on our website confirm our status as a legitimate, verified UK online pharmacy. You can verify our registration at any time via www.pharmacyregulation.org. Our pharmacy team is available for questions before, during, and after your consultation.
References
- Bayer plc. Femodene ED film-coated tablets – Summary of Product Characteristics. Available at: www.medicines.org.uk/emc. Accessed May 2026.
- Faculty of Sexual and Reproductive Healthcare (FSRH). Combined Hormonal Contraception – Clinical Guidance. Available at: www.fsrh.org. Accessed May 2026.
- NHS. Combined pill – your contraception guide. Available at: www.nhs.uk/conditions/contraception/combined-contraceptive-pill. Accessed May 2026.
- British National Formulary (BNF). Ethinylestradiol with gestodene. Available at: bnf.nice.org.uk. Accessed May 2026.
- MHRA. Combined hormonal contraceptives and venous thromboembolism – updated guidance. Available at: www.gov.uk/government/organisations/medicines-and-healthcare-products-regulatory-agency. Accessed May 2026.
Consistent Habit, Continuous Protection
Breaking the daily routine of tablet-taking during a pill-free week might seem like a minor inconvenience, but for some women it is a genuine source of confusion, missed pills, and anxiety about whether they are still protected. Femodene ED addresses this with a straightforward solution: a 28-day pack that contains both active and inactive tablets, so you take a pill every single day without interruption. Femodene ED is a combined oral contraceptive pill licensed in the United Kingdom for the prevention of pregnancy. It contains ethinylestradiol and gestodene, and is designed to be taken as a continuous 28-day cycle with no breaks. This page explains how it works, how to take it correctly, who it is and is not suitable for, and how to access it through a clinical consultation at Pharmacy Planet.
The ED in the name stands for every day. Unlike standard combined pills that involve 21 active tablets followed by a seven-day gap, Femodene ED contains 21 active tablets and seven inactive placebo tablets. You take all 28 in sequence, then start the next pack immediately. Some women find this format helps them stay on a consistent daily schedule, reducing the risk of restarting a new pack late.
Femodene ED is a combined oral contraceptive tablet manufactured by Bayer plc. Each active tablet contains ethinylestradiol 30 micrograms and gestodene 75 micrograms. Ethinylestradiol is a synthetic oestrogen. Gestodene is a synthetic progestogen belonging to the third-generation class of progestogens. The seven inactive tablets in each pack contain no hormones and are included solely to maintain the unbroken daily pill-taking habit.
Femodene ED is a monophasic pill, meaning every active tablet in the pack contains exactly the same dose of both hormones throughout the 28-day cycle. This makes the regimen straightforward: the same tablet every day, with no need to track where you are in a variable-dose schedule.
Femodene ED is a Prescription Only Medicine. It cannot be purchased without a valid prescription from a registered clinician. Before any prescription is issued, a clinical consultation is required to confirm that a combined oestrogen-progestogen pill is appropriate for your health circumstances and to identify any contraindications or risk factors.
Suppressing Ovulation
The primary contraceptive mechanism of Femodene ED is the suppression of ovulation. Ethinylestradiol and gestodene act together on the pituitary gland to inhibit the release of follicle-stimulating hormone and luteinising hormone. Without the luteinising hormone surge that normally triggers egg release, ovulation does not occur. This is the same primary mechanism shared by all combined oral contraceptives.
Secondary Mechanisms
Femodene ED also works through two secondary mechanisms that contribute to its contraceptive effect:
- Gestodene thickens the cervical mucus, making it more difficult for sperm to travel through the cervix.
- The hormonal combination alters the endometrium (the lining of the uterus), reducing its receptiveness to implantation even in the unlikely event that an egg were fertilised.
The Every Day Format
The seven inactive tablets in each Femodene ED pack serve no pharmacological purpose. They are placebo tablets designed to maintain an unbroken daily tablet-taking habit. A withdrawal bleed typically occurs during the seven inactive tablet days due to the drop in hormone levels. This bleed is not a true menstrual period but is a predictable consequence of the brief hormone-free interval.
Cycle Regulation
As a combined hormonal contraceptive, Femodene ED regulates the hormonal signals that govern the menstrual cycle. Many women find that their withdrawal bleeds become lighter and more predictable whilst taking a combined pill. Lighter periods are a recognised secondary effect of combined hormonal contraception and are not a cause for concern.
Starting Your First Pack
Your prescriber will advise on the most appropriate starting day. The standard guidance is:
- Day 1 start: Begin on the first day of your period with the first active tablet. You are protected from pregnancy immediately.
- Day 2 to 5 start: Begin within the first five days of your cycle. Use additional contraception such as condoms for the first seven days.
- Switching from another combined pill: Take the first active Femodene ED tablet the day after your last active tablet from the previous pack. You remain protected immediately. Start from the beginning of the Femodene ED strip.
- Switching from a progestogen-only pill: You can switch on any day. Use additional contraception for the first seven days.
Taking the 28-Day Pack
Take one tablet every day at the same time, working through the pack in the printed sequence. After completing all 28 tablets, begin the next pack immediately the following day. There is no gap between packs.
- Swallow each tablet whole with water.
- Take tablets at the same time each day to maintain consistent hormone levels.
- Take tablets in the correct order as printed on the pack. Active and inactive tablets look different; do not confuse them.
- A withdrawal bleed will usually occur during the seven inactive tablet days. Continue taking tablets every day during this time.
If You Miss a Tablet
The rules differ depending on whether the tablet missed was an active or inactive tablet:
- Missed inactive tablet: no effect on contraceptive protection. Discard the missed inactive tablet and continue with the next tablet as normal.
- Missed one active tablet, fewer than 24 hours late: take the missed tablet immediately and continue as normal. You remain protected.
- Missed one active tablet, more than 24 hours late: take the missed tablet immediately and take the next one at the usual time, even if that means two in one day. Use additional contraception for seven days.
- Missed two or more active tablets: take the most recently missed tablet immediately. Leave other missed tablets. Continue the pack and use additional contraception for seven days. If you missed active tablets in the first week and had unprotected sex, contact your prescriber or pharmacist about emergency contraception.
If vomiting occurs within two hours of taking an active tablet, or if you have severe diarrhoea, treat the situation as a missed pill. Refer to the Patient Information Leaflet for complete missed pill guidance in all specific scenarios.
Tablet Composition
- Active tablets (21 per pack): ethinylestradiol 30 micrograms and gestodene 75 micrograms
- Inactive tablets (7 per pack): no active ingredients
- Monophasic formulation: every active tablet contains the same dose
Pack Format
- Each pack: 28 tablets (21 active and 7 inactive)
- Taken continuously, every day, with no break between packs
Dosage Regimen
One tablet daily at the same time for 28 consecutive days, then begin the next pack immediately. The dose is fixed: 30 micrograms of ethinylestradiol and 75 micrograms of gestodene in each active tablet. There is no titration or dose variation. Your prescriber will confirm the most appropriate starting day for your individual circumstances.
As with all medicines, Femodene ED can cause side effects. Not every woman will experience them. The following is a summary based on the current UK SmPC. Read the Patient Information Leaflet supplied with your medication in full before starting treatment.
Common Side Effects
- Headache or migraine
- Nausea
- Breast tenderness or pain
- Mood changes, including low mood or irritability
- Changes in libido
- Irregular spotting or breakthrough bleeding, especially in the first few cycles
- Changes in vaginal discharge
Less Common Side Effects
- Weight changes
- Changes in contact lens tolerance due to corneal effects
- Skin changes including chloasma (patches of darker skin on the face)
Serious Side Effects: Seek Urgent Medical Attention If You Experience
- Sudden chest pain, shortness of breath, or coughing up blood. These may indicate a pulmonary embolism or heart attack.
- Pain, swelling, or warmth in one leg. This may indicate deep vein thrombosis.
- Sudden severe headache, visual disturbance, weakness in the face, arm, or leg, or difficulty speaking. These may indicate a stroke.
- Severe abdominal pain, which may indicate a liver problem or ectopic pregnancy.
- Jaundice (yellowing of the skin or eyes).
Blood Clot Risk
All combined oral contraceptives carry a small increased risk of venous thromboembolism compared with women not using hormonal contraception. Gestodene-containing pills including Femodene ED are considered to carry a broadly similar VTE risk to desogestrel and drospirenone-containing combined pills, and a somewhat higher risk than levonorgestrel-containing pills. Your prescriber will assess your individual risk factors before prescribing, including BMI, smoking status, personal and family history of blood clots, and any planned periods of immobility.
Important Drug Interactions
Enzyme-inducing medicines can reduce the effectiveness of Femodene ED. These include:
- Rifampicin and rifabutin
- Certain antiepileptic medicines including phenytoin, carbamazepine, phenobarbital, and topiramate
- Some HIV medicines including ritonavir and efavirenz
- St John's Wort
Always disclose your full medication list, including herbal remedies and supplements, at every consultation. If you are prescribed an enzyme-inducing medicine whilst taking Femodene ED, additional contraceptive precautions or an alternative method may be required.
Femodene ED Is Not Suitable If You:
- Have or have ever had a blood clot (deep vein thrombosis, pulmonary embolism, or arterial thrombosis)
- Have or have ever had a stroke or heart attack
- Have migraine with aura
- Have uncontrolled high blood pressure
- Have liver disease or liver tumours
- Have or have ever had breast cancer or another oestrogen-sensitive cancer
- Are pregnant or think you may be pregnant
- Are breastfeeding a baby under six weeks old
- Are a smoker aged 35 or over
- Have diabetes with vascular complications
This Medicine May Be Appropriate If You:
- Are a healthy adult woman seeking reliable daily hormonal contraception
- Find maintaining a daily pill-taking habit easier without a seven-day break in your routine
- Have no personal or family history of blood clots, stroke, or cardiovascular disease
- Do not have migraine with aura and do not smoke heavily
- Are not currently taking medicines that interact significantly with combined oral contraceptives
Use With Caution If You:
- Are a smoker under the age of 35. Smoking increases cardiovascular risk with all oestrogen-containing contraceptives.
- Have a BMI above 30. Obesity is an independent risk factor for VTE.
- Have a family history of blood clots in a first degree relative under the age of 50.
- Have a history of depression. Combined hormonal contraceptives can affect mood in some women.
- Are planning long-haul travel or extended periods of immobility, which independently increase VTE risk.
- Have had high blood pressure during pregnancy or other oestrogen-sensitive conditions in the past.
Pharmacy Planet is a GPhC registered UK online pharmacy. All prescriptions for Femodene ED are issued following a genuine clinical consultation conducted by a registered prescriber. The process works as follows:
- Complete a structured medical questionnaire covering your health history, current medicines, smoking status, BMI, family history of blood clots and cardiovascular disease, and any relevant gynaecological history. Accurate and complete answers are essential.
- A registered prescriber reviews your consultation individually and assesses whether Femodene ED is clinically appropriate for your specific circumstances, including the gestodene-related VTE risk profile.
- A prescription is issued only if the prescriber determines that Femodene ED is appropriate for you. Completing a consultation does not guarantee a prescription. The prescriber may determine that a different contraceptive is more suitable, or that further information or a face-to-face assessment is required.
- If a prescription is issued, your medication is dispensed and dispatched by our pharmacy team. Our team is available for any follow-up questions during or after treatment.
- Repeat supply requires a new consultation to confirm that continued prescribing remains appropriate for your current health.
- Store below 25°C.
- Keep tablets in the original blister pack to protect from moisture.
- Keep this medicine out of the sight and reach of children.
- Do not use tablets after the expiry date printed on the pack.
- Return unused tablets to your pharmacist for safe disposal. Do not dispose of medicines via wastewater or household waste.
This reference guide compares the contraceptive preparations available at Pharmacy Planet, grouped by delivery method and formulation type. Every preparation is a Prescription Only Medicine. A registered prescriber will review your individual health profile, contraceptive history, and risk factors before recommending any preparation. This table is a clinical reference, not a recommendation.
Combined Oral Contraceptive Tablets (Monophasic)
Monophasic combined pills contain the same dose of both hormones in every active tablet. The table below compares commonly prescribed monophasic combined oral contraceptives by progestogen type, oestrogen dose, VTE risk category, pack format, and key clinical characteristics.
| Name | Progestogen | Estrogen | Classification | Dosage Regimen | Description |
|---|---|---|---|---|---|
| Rigevidon | Levonorgestrel 150 mcg | 30 mcg | Lowest | 21+7 | Generic of Microgynon 30 (Consilient Health) |
| Microgynon 30 | Levonorgestrel 150 mcg | 30 mcg | Lowest | 21+7 | Branded originator (Bayer); four-way equivalent family |
| Levest | Levonorgestrel 150 mcg | 30 mcg | Lowest | 21+7 | Generic (Morningside); clinically identical to above |
| Ovranette | Levonorgestrel 150 mcg | 30 mcg | Lowest | 21+7 | Generic (Pfizer); clinically identical to above |
| Microgynon 30 ED | Levonorgestrel 150 mcg | 30 mcg | Lowest | 28 ED | Every-day format; 21 active + 7 placebo tablets |
| Femodene | Gestodene 75 mcg | 30 mcg | Higher | 21+7 | 3rd-gen progestogen; branded originator (Bayer) |
| Femodene ED | Gestodene 75 mcg | 30 mcg | Higher | 28 ED | Every-day format of Femodene; 21 active + 7 placebo |
| Femodette | Gestodene 75 mcg | 20 mcg | Higher | 21+7 | Lower oestrogen version of Femodene |
| Millinette | Gestodene 75 mcg | 30 mcg/20 mcg | Higher | 21+7 | Generic of Femodene (Gedeon Richter) |
| Marvelon | Desogestrel 150 mcg | 30 mcg | Higher | 21+7 | 3rd-gen; branded originator (Organon) |
| Mercilon | Desogestrel 150 mcg | 20 mcg | Higher | 21+7 | Lower oestrogen version of Marvelon |
| Gedarel 30/150 | Desogestrel 150 mcg | 30 mcg | Higher | 21+7 | Generic of Marvelon (Consilient Health) |
| Gedarel 20/150 | Desogestrel 150 mcg | 20 mcg | Higher | 21+7 | Generic of Mercilon (Consilient Health) |
| Lizinna | Norgestimate 250 mcg | 35 mcg | Higher | 21+7 | Generic of discontinued Cilest; prodrug → norelgestromin |
| Cilique | Norgestimate 250 mcg | 35 mcg | Higher | 21+7 | Generic of discontinued Cilest (Consilient Health) |
| Yasmin | Drospirenone 3 mg | 30 mcg | Higher | 28 ED | Branded originator (Bayer); anti-mineralocorticoid activity; potassium interaction – check renal function |
| Lucette | Drospirenone 3 mg | 30 mcg | Higher | 28 ED | Generic of Yasmin (Stragen UK); same potassium interaction |
| Yacella | Drospirenone 3 mg | 30 mcg | Higher | 28 ED | Generic of Yasmin (Stragen UK); same potassium interaction |
| Eloine | Drospirenone 3 mg | 20 mcg | Higher | 28 ED (24+4) | Lower oestrogen; 24 active + 4 inactive; potassium interaction |
| Brevinor | Norethisterone 500 mcg | 35 mcg | Low | 21+7 | 1st-gen progestogen; mild androgenic activity |
| Norimin | Norethisterone 1 mg | 35 mcg | Low | 21+7 | Double norethisterone dose vs Brevinor; same oestrogen |
| Norinyl-1 | Norethisterone 1 mg | Mestranol 50 mcg | Low | 21+7 | Uses mestranol (prodrug) not EE directly; higher oestrogenic exposure than Norimin |
| Dianette (co-cyprindiol) | Cyproterone acetate 2 mg | 35 mcg | Higher | 21+7 | Anti-androgen; licensed for acne and hirsutism; not first-line contraceptive |
| Zoely | Nomegestrol acetate 2.5 mg | Estradiol 1.5 mg | Data limited | 28 ED (24+4) | Natural oestrogen (hemihydrate); 12-hour missed pill window; no generic |
Important: This comparison is for general information only and does not replace medical advice. A prescriber will decide which treatment is suitable for you following an online consultation.
Pharmacy Planet is a registered UK online pharmacy regulated by the General Pharmaceutical Council. We provide a clinically responsible and confidential route to accessing prescription contraception, including everyday combined pills such as Femodene ED. Our platform supports informed decision-making, with genuine clinical assessment at every stage.
Every prescriber working through our platform reviews consultations individually. They make clinical decisions based on your specific health profile, and if Femodene ED is not appropriate for you, they will tell you clearly. Our team will support you in exploring alternatives wherever that is possible. Clinical integrity is a feature of our service, not an inconvenience.
Our GPhC registration and the EU common logo on our website confirm our status as a legitimate, verified UK online pharmacy. You can verify our registration at any time via www.pharmacyregulation.org. Our pharmacy team is available for questions before, during, and after your consultation.
- Bayer plc. Femodene ED film-coated tablets – Summary of Product Characteristics. Available at: www.medicines.org.uk/emc. Accessed May 2026.
- Faculty of Sexual and Reproductive Healthcare (FSRH). Combined Hormonal Contraception – Clinical Guidance. Available at: www.fsrh.org. Accessed May 2026.
- NHS. Combined pill – your contraception guide. Available at: www.nhs.uk/conditions/contraception/combined-contraceptive-pill. Accessed May 2026.
- British National Formulary (BNF). Ethinylestradiol with gestodene. Available at: bnf.nice.org.uk. Accessed May 2026.
- MHRA. Combined hormonal contraceptives and venous thromboembolism – updated guidance. Available at: www.gov.uk/government/organisations/medicines-and-healthcare-products-regulatory-agency. Accessed May 2026.
ED stands for every day. Femodene ED is formulated as a 28-day pack containing 21 active hormone tablets and 7 inactive placebo tablets. You take one tablet every day throughout the 28-day pack and then start the next pack immediately, without any break. The inactive tablets serve no hormonal purpose. They are included to help you maintain an unbroken daily tablet-taking habit. When the active tablets run out and you take the inactive ones, a withdrawal bleed usually occurs. This every day format differs from standard combined pills, which involve a seven-day tablet-free gap between packs.
When taken correctly and consistently, Femodene ED is over 99% effective at preventing pregnancy. This level of effectiveness applies to all combined oral contraceptives used as directed. In typical use, which accounts for occasionally missed or late tablets, effectiveness is somewhat lower. Taking your tablet at the same time every day and following the missed pill guidance carefully maximises protection. The every day format may help some women maintain consistent daily use by removing the need to restart after a break.
Gestodene is a third-generation synthetic progestogen used in several combined contraceptive pills including Femodene ED. It differs from older progestogens such as levonorgestrel and norethisterone in its hormonal selectivity. Gestodene-containing pills are considered to carry a slightly higher VTE risk than pills containing levonorgestrel, but a broadly similar risk to those containing desogestrel or drospirenone. The MHRA has issued guidance on this risk profile. Your prescriber will take the type of progestogen into account when assessing which combined pill is most appropriate for your individual risk factors.
If you miss an inactive (placebo) tablet, this has no effect on your contraceptive protection. Simply discard the missed tablet and continue. If you miss one active tablet and are fewer than 24 hours late, take it immediately and continue as normal. If you are more than 24 hours late, take the missed active tablet immediately, continue the pack, and use additional contraception for seven days. If you miss two or more active tablets, take the most recently missed one immediately, leave the others, continue the pack, and use additional contraception for seven days. Contact your prescriber about emergency contraception if you missed tablets in the first week and had unprotected sex.
Most women taking Femodene ED experience a withdrawal bleed during the seven inactive tablet days. This bleed is caused by the drop in hormone levels when you take the inactive tablets and is not a true menstrual period. Withdrawal bleeds on combined pills are often lighter and shorter than natural periods. Some women experience irregular spotting, particularly in the first one to three cycles, as the body adjusts to the new hormonal pattern. This is common when starting any combined pill and usually settles. If you experience very heavy or prolonged bleeding at any point, contact your prescriber.
If you experience migraine with aura, Femodene ED is contraindicated. All oestrogen-containing combined pills, including Femodene ED, are associated with an increased risk of stroke in women who experience aura, regardless of how low the oestrogen dose is. This is an absolute contraindication. If you experience migraine without aura, your prescriber will conduct an individual assessment before deciding whether to prescribe. Always disclose your full migraine history during your consultation, including whether you experience any visual disturbances, sensory changes, or speech difficulties before or during your headaches.
Yes. Standard Femodene contains the same active ingredients (ethinylestradiol 30 micrograms and gestodene 75 micrograms) as Femodene ED, but comes in a 21-tablet pack with no inactive tablets. With standard Femodene, you take 21 active tablets and then have a seven-day tablet-free interval before starting the next pack. Femodene ED adds seven inactive placebo tablets so you take a tablet every day without a break, then start the next pack immediately. The contraceptive content and clinical effect are the same. The difference is purely in how the pack is formatted and how you manage the transition between packs.
It is possible to skip a withdrawal bleed by running packs together: simply start a new pack of Femodene ED on day 22 without taking the seven inactive tablets from your current pack. Many women do this for practical reasons such as holidays or special events. However, running packs together on Femodene ED requires you to understand which tablets are active and which are inactive, and to plan accordingly. There is a higher chance of irregular spotting when running packs together. Discuss this approach with your prescriber before trying it for the first time, particularly if you are new to this pill.
Weight gain is not listed as a common side effect in the current UK SmPC for Femodene ED. Robust clinical evidence has not consistently demonstrated a direct causal link between combined oral contraceptives and significant weight gain. Some women notice temporary fluid retention or breast fullness when starting a combined pill. If you experience significant or persistent weight changes after starting Femodene ED, discuss this with your prescriber or GP. They can assess whether the pill is likely to be contributing and advise on alternatives if appropriate.
Fertility typically returns quickly after stopping Femodene ED. Most women ovulate within one to three months of stopping the combined pill, and there is no clinical evidence that taking the pill long-term reduces fertility. Some women conceive within their first natural cycle after stopping, while others take a few months for their cycle to regularise. If you are planning a pregnancy, stop the pill and allow your cycle to return naturally before conceiving. This makes it easier to date the pregnancy accurately. If you have not had a period within three months of stopping, speak to your GP.
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Review By
GURDEV SEHMI
Last Updated On : Mar 13 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925
Authored By
GURDEV SEHMI
Last Reviewed On : Mar 23 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925


