Jentadueto
Jentadueto is a blood sugar lowering medicine that is prescribed for type 2 diabetes. The active substances in this medicine are linagliptin and metformin. Type 2 diabetes is a condition in which the pancreas does not make enough insulin and the muscles and liver do not respond adequately to insulin. As a result, the sugar in food is not processed well and the blood sugar level rises. Type 2 diabetes causes symptoms such as thirst, frequent urination, tiredness, poor wound healing, and dry mouth. Doctors often prescribe metformin or another medication in the category of DPP 4 inhibitors, such as linagliptin. If these medications don't work well on their own, a combination of medication may help. Jentadueto contains metformin and linagliptin. These substances lower blood sugar levels by controlling insulin levels. They also ensure that the body produces less glucose after eating. Metformin also inhibits the feeling of hunger.
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Select your preferred options and see the best price
| Pack | Price (£) | ||
|---|---|---|---|
| - | 2.5mg/850mg | 56 Tablets | 55.20 |
| - | 2.5mg/850mg | 112 Tablets | 105.80 |
| - | 2.5mg/850mg | 168 Tablets | 143.75 |
| - | 2.5mg/1000mg | 56 Tablets | 55.20 |
| - | 2.5mg/1000mg | 112 Tablets | 105.80 |
| - | 2.5mg/1000mg | 168 Tablets | 143.75 |
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Jentadueto Tablets for Type 2 Diabetes Blood Sugar Control
Sometimes metformin alone is not quite enough. Your blood sugar improves, but not enough to reach target levels. That is often when combination treatment is considered.
Jentadueto Tablets combine metformin with linagliptin, a medicine known as a DPP-4 inhibitor. DPP-4 inhibitors work by increasing natural hormones that control blood sugar after meals. By bringing linagliptin and metformin together in one tablet, Jentadueto simplifies daily treatment while delivering stronger and more balanced glucose management. Jentadueto is used in adults with type 2 diabetes when diet, exercise, and metformin alone are not providing the blood sugar control needed.
How Do Jentadueto Tablets Work?
Jentadueto works in two different ways.
Linagliptin: Increases natural hormone activity after meals, encourages insulin release when blood sugar rises, and reduces glucagon release, helping lower glucose production when blood sugar is high.
Metformin: Reduces glucose production in the liver and improves the body's response to insulin.
By combining both, Jentadueto offers steady blood sugar control throughout the day without adding extra tablets. Jentadueto contains the same active ingredients as taking both medicines separately, meaning fewer tablets to remember each day, a more consistent routine, and no loss of strength or effectiveness.
When Are Jentadueto Tablets Prescribed?
Jentadueto is suitable for adults with type 2 diabetes when metformin alone is not enough, when already taking linagliptin and metformin separately, and alongside other diabetes medication, including insulin, if additional support is required. If used with insulin or a sulfonylurea, doses of those medicines may need adjusting to reduce the risk of low blood sugar.
How to Take Jentadueto Tablets
Jentadueto is taken twice daily with meals. Taking it with food reduces stomach upset linked to metformin.
Available strengths:
- Jentadueto 2.5mg/850mg
- Jentadueto 2.5mg/1000mg
The dose is based on your current metformin dose, how well your blood sugar is controlled, and kidney function. The maximum daily dose is 5 mg linagliptin and 2,000 mg metformin. If you miss a dose, take it when remembered unless it is nearly time for the next one. Do not take two tablets together.
As Jentadueto contains metformin, kidney function must be checked before starting and monitored regularly. Jentadueto is not initiated if eGFR is below 30 mL/min/1.73m². If eGFR falls below 45 mL/min/1.73m², dose review and closer monitoring may be required. Treatment may be paused during dehydration, severe illness, or before certain scans.
Who Cannot Use Jentadueto Tablets?
Jentadueto tablets are not suitable if you have type 1 diabetes, diabetic ketoacidosis, severe kidney failure, severe liver disease, conditions linked to low oxygen levels such as unstable heart failure, or if you are pregnant, planning pregnancy, or breastfeeding. Suitability is confirmed during consultation with Pharmacy Planet.
Possible Side Effects of Jentadueto Tablets
Like all diabetes combination pills, side effects can occur while taking Jentadueto tablets.
Common Side Effects:
- Nausea
- Diarrhoea
- Stomach discomfort
- Mild cold-like symptoms
These often settle after the first few weeks.
Serious Side Effects:
- Severe stomach pain that spreads to the back, which may indicate pancreatitis
- Unusual tiredness with breathing difficulty or muscle pain, which may signal lactic acidosis
- Signs of an allergic skin reaction with blistering
- Symptoms of low blood sugar when used with insulin or sulfonylureas
Although rare, these reactions require immediate assessment.
Why Do People Choose Jentadueto Tablets?
People often choose Jentadueto because it combines two diabetes medications into one tablet, simplifies oral diabetic therapy, supports stronger glucose management than metformin alone, is generally weight-neutral and not associated with weight gain, and fits easily into a twice-daily routine. For many, fewer tablets mean better adherence and steadier sugar control.
Order Jentadueto Tablets from Pharmacy Planet
Getting Jentadueto tablets online from Pharmacy Planet is straightforward and supervised.
- Complete the online consultation and share details about your type 2 diabetes, current medication, and recent blood sugar readings.
- A UK-registered prescriber checks safety and dosing suitability.
- If approved, your Jentadueto tablets are dispensed and delivered discreetly to your address.
Sometimes metformin alone is not quite enough. Jentadueto Tablets combine metformin with linagliptin, a DPP-4 inhibitor, to simplify daily treatment while delivering stronger and more balanced glucose management.
Jentadueto is used in adults with type 2 diabetes when diet, exercise, and metformin alone are not providing the blood sugar control needed.
Linagliptin: Increases natural hormone activity after meals, encourages insulin release when blood sugar rises, and reduces glucagon release.
Metformin: Reduces glucose production in the liver and improves the body's response to insulin.
By combining both, Jentadueto offers steady blood sugar control throughout the day without adding extra tablets.
Jentadueto is suitable for adults with type 2 diabetes when metformin alone is not enough, when already taking linagliptin and metformin separately, or alongside other diabetes medication including insulin when additional support is required.
Taken twice daily with meals. Available in 2.5mg/850mg and 2.5mg/1000mg strengths. Maximum daily dose: 5mg linagliptin and 2,000mg metformin. Do not take two tablets together if a dose is missed.
Kidney function must be checked before starting and monitored regularly. Not initiated if eGFR is below 30 mL/min/1.73m².
Not suitable if you have: type 1 diabetes, diabetic ketoacidosis, severe kidney failure, severe liver disease, conditions linked to low oxygen levels such as unstable heart failure, or if you are pregnant, planning pregnancy, or breastfeeding.
Common Side Effects:
- Nausea, diarrhoea, stomach discomfort, mild cold-like symptoms
Serious Side Effects:
- Severe stomach pain spreading to the back (possible pancreatitis)
- Unusual tiredness with breathing difficulty or muscle pain (possible lactic acidosis)
- Allergic skin reaction with blistering
- Low blood sugar when used with insulin or sulfonylureas
These reactions are rare but require immediate assessment.
People often choose Jentadueto because it combines two diabetes medications into one tablet, simplifies oral diabetic therapy, supports stronger glucose management than metformin alone, is generally weight-neutral, and fits easily into a twice-daily routine.
Getting Jentadueto tablets online from Pharmacy Planet is straightforward and supervised.
- Complete the online consultation and share details about your type 2 diabetes, current medication, and recent blood sugar readings.
- A UK-registered prescriber checks safety and dosing suitability.
- If approved, your Jentadueto tablets are dispensed and delivered discreetly to your address.
Jentadueto contains both linagliptin and metformin. It is usually prescribed when metformin alone is not enough. The added linagliptin improves blood sugar control after meals.
Both are combination diabetes tablets, but Jentadueto contains linagliptin plus metformin, while Janumet contains sitagliptin plus metformin. They belong to the same medicine class but are different drugs.
Jentadueto is not linked to weight gain. Metformin is weight-neutral, and linagliptin does not usually increase body weight.
There is a small risk of pancreatitis with linagliptin. Severe and ongoing stomach pain that spreads to the back should be checked urgently.
Jentadueto contains metformin, which is removed through the kidneys. Regular kidney checks ensure the medicine does not build up in the body.
Yes. Jentadueto is often prescribed for people already taking both medicines separately. The dose usually matches the amounts you were already taking.
On its own, Jentadueto rarely causes low blood sugar. The risk increases if taken with insulin or sulfonylureas.
Excess alcohol increases the risk of lactic acidosis due to the metformin component. Heavy drinking should be avoided.
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Review By
GURDEV SEHMI
Last Updated On : Mar 13 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925
Authored By
GURDEV SEHMI
Last Reviewed On : Mar 23 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925


