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Synjardy (Empagliflozin and metformin) is a combination medicine that is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. Empagliflozin and metformin are also used to decrease the risk of death from a heart attack, stroke, or heart failure in adults with type 2 diabetes who also have heart disease. Empagliflozin belongs to a group of medicines called sodium-glucose cotransporter inhibitors type 2 (SGLT2). It works by blocking the SGLT2 protein in the kidneys. This causes the removal of sugar (glucose) from the blood in the urine. Metformin works differently to lower blood glucose levels, mainly by blocking glucose production in the liver. Consequently, Synjardy reduces the amount of sugar in the blood. This medication can help prevent heart disease.

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Price Comparison

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Pack Price (£)
- 12.5mg/850mg 56 Tablets 96.00
- 12.5mg/850mg 112 Tablets 184.00
- 12.5mg/850mg 168 Tablets 241.00
- 5mg/850mg 56 Tablets 96.00
- 5mg/850mg 112 Tablets 184.00
- 5mg/850mg 168 Tablets 241.00
- 12.5mg/1000mg 56 Tablets 96.00
- 12.5mg/1000mg 112 Tablets 184.00
- 12.5mg/1000mg 168 Tablets 241.00
- 5mg/1000mg 56 Tablets 96.00
- 5mg/1000mg 112 Tablets 184.00
- 5mg/1000mg 168 Tablets 241.00

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Synjardy Tablets for Type 2 Diabetes Blood Sugar Control

Managing type 2 diabetes often requires more than one medicine. For some people, a single treatment may not provide enough blood sugar control on its own.

Synjardy tablets combine two widely used diabetes medicines, empagliflozin and metformin, into one tablet. This approach simplifies treatment while supporting stronger glucose management throughout the day. By bringing these medicines together, Synjardy works as a combination diabetes tablet designed to support daily diabetic care in adults whose blood sugar levels remain high despite diet, exercise, or other diabetes medication.

What Are Synjardy Tablets?

Synjardy tablets are combination diabetes tablets used for adults with type 2 diabetes. Each tablet contains empagliflozin and metformin, two medicines that work in different ways to improve blood sugar control. These diabetes combo pills are often prescribed when metformin alone does not provide adequate glucose management, when a patient is already taking empagliflozin and metformin separately, or when additional oral diabetes therapy is needed to improve sugar levels. Using a combination tablet can make treatment simpler by reducing the number of medicines taken each day.

How Do Synjardy Tablets Work?

The two medicines in Synjardy work together to support better glucose management. Empagliflozin works by helping the kidneys remove excess sugar from the body through urine. Metformin reduces the amount of sugar produced by the liver and improves how the body uses insulin.

Together, this dual action supports improved blood sugar control, better day-to-day diabetic care, and a more consistent approach to managing type 2 diabetes. As the medicines act in different ways, they complement each other in maintaining healthy sugar levels.

How to Take Synjardy Tablets

Synjardy is usually taken twice daily with meals. Swallow the tablet whole with water. Take doses with food to reduce stomach discomfort. Follow the exact dose recommended by your prescriber. The strength of empagliflozin and metformin in the tablet may vary depending on the individual treatment plan.

If a dose is missed, take it as soon as you remember. If it is close to the next dose, skip the missed tablet. Do not take two tablets at the same time. Taking extra doses does not improve blood sugar control and may increase side-effect risk.

Who Can Use Synjardy Tablets?

Synjardy is prescribed for people with type 2 diabetes who need stronger support with blood sugar control. It may be used when metformin alone is not enough to control sugar levels, alongside other diabetes medication if additional glucose control is required, or as a replacement for taking empagliflozin and metformin separately.

This medicine may not be suitable for individuals who:

  • Have type 1 diabetes.
  • Have severe kidney problems.
  • Have severe liver impairment.
  • Have experienced diabetic ketoacidosis.
  • Have a history of metabolic acidosis.

People with certain heart, kidney, or metabolic conditions may require careful assessment before starting oral diabetes therapy with Synjardy.

Possible Side Effects of Synjardy Tablets

Like all diabetes medication, Synjardy can cause side effects.

Common Side Effects:

  • Stomach discomfort or nausea
  • Diarrhoea
  • Increased urination
  • Mild urinary or genital infections

These effects are usually mild and often settle as the body adjusts to treatment.

Serious Side Effects:

  • Signs of lactic acidosis, including severe tiredness, muscle pain, or breathing difficulty
  • Symptoms of diabetic ketoacidosis, such as nausea, vomiting, stomach pain, or confusion
  • Severe dehydration or dizziness

Although uncommon, these reactions require immediate medical care.

Why Do People Choose Synjardy Tablets?

Many people with type 2 diabetes reach a stage where one medicine alone does not provide the level of blood sugar control they need. People prefer Synjardy because it combines empagliflozin and metformin in a single tablet, supports stronger and more consistent glucose management, reduces the need to take multiple diabetes medications separately, and fits easily into daily oral diabetes therapy routines. For many patients, these combination diabetes tablets simplify treatment while supporting long-term diabetic care and more stable sugar levels.

How Does the Ordering Process Work at Pharmacy Planet?

Starting treatment with Synjardy tablets is designed to be quick and straightforward while still ensuring the right medical checks are in place.

  1. Complete a short consultation and provide details about your diabetes history, current medication, and overall health.
  2. A qualified prescriber reviews your information to check whether Synjardy tablets are appropriate for your diabetes treatment plan.
  3. Once approved, your combination diabetes tablets are delivered by the pharmacy securely to your address.
Synjardy Tablets

Synjardy tablets combine two widely used diabetes medicines, empagliflozin and metformin, into one tablet. This approach simplifies treatment while supporting stronger glucose management throughout the day.

Synjardy is designed to support daily diabetic care in adults whose blood sugar levels remain high despite diet, exercise, or other diabetes medication.

Synjardy tablets are combination diabetes tablets for adults with type 2 diabetes. Each tablet contains empagliflozin and metformin, two medicines that work in different ways to improve blood sugar control. Often prescribed when metformin alone is insufficient or when a patient already takes both medicines separately.

Empagliflozin helps the kidneys remove excess sugar from the body through urine. Metformin reduces the amount of sugar produced by the liver and improves how the body uses insulin. Together, this dual action supports improved blood sugar control and better day-to-day diabetic care.

Taken twice daily with meals. Swallow whole with water. Take with food to reduce stomach discomfort. Follow your prescriber's exact dose. If a dose is missed, take it when remembered unless it is close to the next dose — do not take two tablets at once.

For adults with type 2 diabetes needing stronger blood sugar support. May not be suitable for people with: type 1 diabetes, severe kidney problems, severe liver impairment, diabetic ketoacidosis, or a history of metabolic acidosis. Careful assessment required for those with certain heart, kidney, or metabolic conditions.

Common Side Effects:

  • Stomach discomfort or nausea, diarrhoea, increased urination, mild urinary or genital infections

Serious Side Effects:

  • Signs of lactic acidosis (severe tiredness, muscle pain, breathing difficulty)
  • Symptoms of diabetic ketoacidosis (nausea, vomiting, stomach pain, confusion)
  • Severe dehydration or dizziness

These reactions require immediate medical care.

People prefer Synjardy because it combines empagliflozin and metformin in a single tablet, supports stronger glucose management, reduces the need for multiple separate medicines, and fits easily into daily oral diabetes therapy routines.

Starting treatment with Synjardy tablets is quick and straightforward.

  1. Complete a short consultation and provide details about your diabetes history, current medication, and overall health.
  2. A qualified prescriber reviews your information to check whether Synjardy is appropriate.
  3. Once approved, your tablets are delivered securely to your address.
Frequently Asked Questions

Synjardy tablets are used to treat type 2 diabetes. They combine empagliflozin and metformin to improve blood sugar control when lifestyle changes or other diabetes medicines are not enough.

Empagliflozin removes excess sugar through urine, while metformin reduces sugar production in the liver and improves insulin use. Together they support stronger glucose management.

Yes. Many patients switch to Synjardy tablets if they are already taking empagliflozin and metformin separately. This combination can simplify daily oral diabetes therapy.

Synjardy is normally taken twice daily with meals. Taking the tablets with food reduces stomach upset linked to the metformin component.

Synjardy alone usually does not cause hypoglycaemia. However, the risk may increase if it is taken with insulin or certain sugar-control tablets such as sulphonylureas.

Yes. As empagliflozin removes glucose through urine, some people notice increased urination. This effect is linked to how the medicine improves blood sugar control.

Kidney function must be checked before starting Synjardy. Severe kidney disease may make this diabetes combo pill unsuitable.

When combined with healthy eating and physical activity, Synjardy supports consistent glucose management and improves overall diabetic care.

No. Synjardy tablets are only used for type 2 diabetes and are not suitable for treating type 1 diabetes.

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Review By

HARMINDER ‘HARMY’ KAUR

Last Updated On : Mar 13 2026

BSc(hons) Pharmacy

GPhC Number: 2061107

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Authored By

GURDEV SEHMI

Last Reviewed On : Mar 23 2026

BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead

GPhC Number: 2050925