Invokana
Invokana is an antidiabetic medicine whose active substance is canagliflozin. It's used in adults with type 2 diabetes, to control the concentration of glucose (sugar) in the blood. Invokana can be administered as monotherapy in patients whose blood glucose levels are not controlled satisfactorily only through diet and exercise and cannot take metformin (another antidiabetic). Canagliflozin is an orally active SGLT2 inhibitor. By inhibiting SGLT2, canagliflozin decreases reabsorption of filtered glucose and lowers the renal glucose threshold (URG), thereby increasing EUG and lowering previously elevated plasma glucose concentrations by this insulin-independent mechanism in patients with type 2 diabetes.
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| Pack | Price (£) | ||
|---|---|---|---|
| - | 100mg | 30 Tablets | 64.40 |
| - | 100mg | 60 Tablets | 123.00 |
| - | 100mg | 90 Tablets | 174.80 |
| - | 300mg | 30 Tablets | 64.40 |
| - | 300mg | 60 Tablets | 123.00 |
| - | 300mg | 90 Tablets | 174.80 |
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Invokana Tablets for Type 2 Diabetes Blood Sugar Control
If you're managing type 2 diabetes and your numbers still swing up and down despite decent habits, you're not alone. Invokana tablets are designed to support steady glucose management alongside diet and exercise.
Invokana contains canagliflozin, an SGLT2 inhibitor that lowers blood sugar in a different way than many other diabetes tablets. It works through the kidneys, helping your body remove excess glucose through urine. For many people, that means an added layer of control as part of long-term diabetes care.
What Is Invokana? How Does It Work?
Invokana (canagliflozin) is a prescription oral diabetes treatment used in adults with type 2 diabetes. It belongs to a group of medicines called SGLT2 inhibitors. Instead of increasing insulin, it blocks the SGLT2 protein in the kidneys, reduces the amount of glucose reabsorbed back into the bloodstream, increases the amount of sugar passed out in urine, and supports overall blood sugar control throughout the day.
As it works independently of insulin, Invokana can be used alone or alongside other diabetic medications when needed.
Beyond Sugar Control: Heart and Kidney Protection
Invokana is not only used for glucose management. In adults with type 2 diabetes and established cardiovascular disease, when prescribed according to licensed indications, Invokana may reduce the risk of heart attack, stroke, and cardiovascular death.
In adults with diabetic kidney disease and protein in the urine, Invokana may reduce the risk of worsening kidney function, end-stage kidney disease (ESKD), and hospitalisation for heart failure. For some people, this wider protection is an important part of long-term diabetes care.
How to Take Invokana Tablets
Invokana tablets are taken once daily, usually before the first meal of the day. Your prescriber will decide the right strength based on your current blood sugar levels, kidney function, and other diabetes medication you are taking.
Invokana should always be used alongside a balanced diet and regular physical activity. Do not use Invokana for type 1 diabetes. Suitability depends on your kidney function (eGFR), and Invokana may not be started or may need dose adjustment if kidney function is significantly reduced.
Who Can Use Invokana Tablets?
Invokana may be suitable for:
- Adults with type 2 diabetes needing improved blood sugar control.
- Adults with type 2 diabetes and heart disease.
- Adults with diabetic kidney disease and protein in the urine.
Invokana is not suitable if you:
- Have type 1 diabetes.
- Have significantly reduced kidney function (based on eGFR assessment).
- Are allergic to canagliflozin.
A full medical review is always required before starting treatment.
Important Safety Information About Invokana
Like all sugar-lowering tablets, Invokana can cause side effects. Most are manageable, but some may need urgent medical attention.
Common Side Effects:
- Dehydration, which may cause dizziness or fainting
- Genital yeast infections
- Urinary tract infections
- Increased urination, especially at night
- Low blood sugar when taken with insulin or sulfonylureas
Staying well hydrated and checking your feet regularly are important parts of safe treatment while taking Invokana.
Serious Side Effects — Seek immediate medical attention if you notice:
- Symptoms of diabetic ketoacidosis, such as nausea, vomiting, stomach pain, unusual tiredness, or breathing difficulty
- Signs of a serious allergic reaction, such as swelling of the face, lips, tongue, or throat
- Severe pain, redness, or swelling around the genitals or anal area
- New sores, ulcers, tenderness, or infections in your legs or feet
Canagliflozin has been linked in some studies to an increased risk of lower limb amputation, particularly in people with circulation problems, nerve damage, or previous foot ulcers.
Why Do People Choose Invokana Tablets?
Many people choose Invokana as part of a modern oral diabetes treatment plan because it works independently of insulin, supports consistent blood sugar control, offers additional heart and kidney benefits for eligible patients, is taken once daily, and fits into long-term diabetes care plans. For those who need more than diet and exercise alone, Invokana can be a practical and clinically supported option.
Order Invokana Tablets from Pharmacy Planet
Getting Invokana online from Pharmacy Planet is simple and clinically supervised.
- Complete the online consultation and share details about your type 2 diabetes, current medicines, and medical history.
- A UK-registered prescriber checks if Invokana is suitable for your condition.
- If approved, your Invokana tablets are dispensed and delivered discreetly to your address.
Your safety always comes first, and treatment is only supplied when clinically appropriate.
If you're managing type 2 diabetes and your numbers still swing up and down despite decent habits, you're not alone. Invokana tablets are designed to support steady glucose management alongside diet and exercise.
Invokana contains canagliflozin, an SGLT2 inhibitor that lowers blood sugar in a different way than many other diabetes tablets. It works through the kidneys, helping your body remove excess glucose through urine.
Invokana (canagliflozin) is a prescription oral diabetes treatment used in adults with type 2 diabetes. It belongs to a group of medicines called SGLT2 inhibitors. Instead of increasing insulin, it blocks the SGLT2 protein in the kidneys, reduces glucose reabsorbed into the bloodstream, increases sugar passed out in urine, and supports blood sugar control throughout the day.
As it works independently of insulin, Invokana can be used alone or alongside other diabetic medications when needed.
Invokana is not only used for glucose management. In adults with type 2 diabetes and established cardiovascular disease, it may reduce the risk of heart attack, stroke, and cardiovascular death when prescribed according to licensed indications.
In adults with diabetic kidney disease and protein in the urine, it may reduce the risk of worsening kidney function, end-stage kidney disease (ESKD), and hospitalisation for heart failure.
Taken once daily, usually before the first meal of the day. Your prescriber will decide the right strength based on your blood sugar levels, kidney function, and other diabetes medications you are taking.
Always use alongside a balanced diet and regular physical activity. Do not use for type 1 diabetes. Suitability depends on kidney function (eGFR).
May be suitable for:
- Adults with type 2 diabetes needing improved blood sugar control.
- Adults with type 2 diabetes and heart disease.
- Adults with diabetic kidney disease and protein in the urine.
Not suitable if you:
- Have type 1 diabetes.
- Have significantly reduced kidney function (based on eGFR assessment).
- Are allergic to canagliflozin.
Common Side Effects:
- Dehydration (dizziness/fainting), genital yeast infections, urinary tract infections, increased urination, low blood sugar with insulin or sulfonylureas
Serious Side Effects — Seek immediate medical attention for:
- Symptoms of diabetic ketoacidosis (nausea, vomiting, stomach pain, unusual tiredness, breathing difficulty)
- Serious allergic reaction (facial/lip/tongue/throat swelling)
- Severe pain, redness or swelling around the genitals or anal area
- New sores, ulcers, or infections in legs or feet
Canagliflozin has been linked to an increased risk of lower limb amputation in people with circulation problems or previous foot ulcers.
Many people choose Invokana because it works independently of insulin, supports consistent blood sugar control, offers additional heart and kidney benefits for eligible patients, is taken once daily, and fits into long-term diabetes care plans.
Getting Invokana online from Pharmacy Planet is simple and clinically supervised.
- Complete the online consultation and share details about your type 2 diabetes, current medicines, and medical history.
- A UK-registered prescriber checks if Invokana is suitable for your condition.
- If approved, your Invokana tablets are dispensed and delivered discreetly to your address.
Invokana works through your kidneys. It blocks a protein called SGLT2, which causes extra glucose to leave your body in urine instead of staying in your bloodstream.
Yes, it often does. As Invokana removes sugar through urine, you may notice you pass urine more frequently, especially in the first few weeks.
Some people lose a small amount of weight while taking Invokana. This happens because excess sugar (and calories) is passed out in urine.
In eligible adults with type 2 diabetes and established cardiovascular disease, Invokana may reduce the risk of heart attack, stroke, and progression of kidney disease when prescribed appropriately.
Invokana can rarely cause diabetic ketoacidosis, even if blood sugar is not extremely high. Symptoms include nausea, stomach pain, and fast breathing. This needs urgent medical care.
As more sugar leaves the body through urine, it creates an environment where yeast can grow more easily. Genital yeast infections are a known side effect.
Yes, it may need to be stopped before surgery or if you are fasting for a long time. This reduces the risk of dehydration and ketoacidosis. Always follow the prescriber's advice.
Yes, but blood sugar can drop too low when combined. Your dose of insulin or sulfonylurea may need adjustment to prevent hypoglycaemia.
Invokana is not suitable for people with type 1 diabetes, significantly reduced kidney function (based on eGFR assessment), or those allergic to canagliflozin.
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Review By
HARMINDER ‘HARMY’ KAUR
Last Updated On : Mar 13 2026
BSc(hons) Pharmacy
GPhC Number: 2061107
Authored By
GURDEV SEHMI
Last Reviewed On : Mar 23 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925


