Competact
Competact is a medicine that reduces the level of glucose (sugar) in the blood. This medicine consists of 2 active ingredients: Metformin ensures that more glucose is absorbed into the liver through the muscles. Pioglitazone speeds up the absorption of glucose in the body's cells and prevents the liver from releasing too much glucose into the blood. The combination of these medicines contained in Competact lowers blood sugar levels. Competact is prescribed to patients with type 2 diabetes mellitus. This is a form of diabetes in which the liver and muscles respond less to insulin. This increases the blood glucose content. An excessive level of sugar in the blood causes symptoms such as thirst, tiredness, blurred vision, and an increased need to urinate. In addition, the organs can be damaged by the higher content of sugar in the blood. Competact lowers blood sugar level and reduces type 2 symptoms.
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| Pack | Price (£) | ||
|---|---|---|---|
| - | 15mg/850mg | 56 Tablets | 62.00 |
| - | 15mg/850mg | 112 Tablets | 112.00 |
| - | 15mg/850mg | 168 Tablets | 149.00 |
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Competact Tablets for Type 2 Diabetes Treatment
When one medicine is no longer enough to keep blood sugar stable, Competact tablets offer a combined approach in a single tablet. Competact is used in adults with type 2 diabetes who are already stabilised on treatment with pioglitazone and metformin given as separate tablets and who require continued combination therapy to maintain adequate blood sugar control.
Each tablet contains 15mg pioglitazone and 850mg metformin hydrochloride. This fixed combination simplifies diabetes management by reducing the need for multiple separate tablets. If approved following an online consultation, you can order Competact tablets securely from Pharmacy Planet.
What Is Competact? How Does It Work?
Competact combines two medicines with complementary actions: pioglitazone (an insulin sensitiser from the thiazolidinedione group) and metformin (a biguanide used as a first-line diabetes treatment).
- Pioglitazone improves insulin sensitivity in muscle, fat, and liver cells.
- Metformin reduces glucose production in the liver and improves peripheral glucose uptake.
This dual mechanism strengthens glucose regulation when metformin alone is no longer enough.
Why Is Competact Used as a Second-Line Treatment?
Competact tablets are usually used when blood sugar remains high despite treatment with metformin and pioglitazone as separate tablets, when a combined oral diabetes therapy is more practical, or when better HbA1c reduction is needed for improved diabetes management.
Combination therapy has been shown to improve glycaemic control compared with monotherapy in patients inadequately controlled. Your response will be reviewed after 3 to 6 months to ensure the treatment continues to provide benefit.
How to Take Competact Tablets
Competact is a prescription-only medicine for adults aged 18 years and over.
Dosage Guidance:
- Usual recommended dose: one Competact 15mg/850mg tablet twice daily.
- This provides 30mg pioglitazone and 1,700mg metformin per day.
- Take with or just after food, swallowed whole with a glass of water.
- Taking it with meals reduces stomach discomfort associated with metformin.
- Not recommended for children or adolescents under 18 years.
Who Should Not Take Competact Tablets?
Competact is not suitable if you have:
- Current or previous heart failure.
- Bladder cancer or unexplained blood in urine.
- Severe kidney failure (GFR below 30 mL/min).
- Liver impairment.
- Diabetic ketoacidosis or diabetic pre-coma.
- Acute alcohol intoxication or alcoholism.
It should also be temporarily stopped before certain imaging procedures using contrast dye and during major surgery. Kidney function must be checked before starting and monitored regularly throughout treatment.
Possible Side Effects of Competact Tablets
Like all medicines, Competact may cause side effects ranging from common to serious.
Common Side Effects:
- Stomach upset, nausea, or diarrhoea
- Weight gain
- Swelling (oedema)
- Headache
- Reduced vitamin B12 levels with long-term use
Serious Side Effects:
- Signs of heart failure
- Severe allergic reaction
- Liver problems (yellowing of skin or eyes)
- Lactic acidosis (very rare)
- Increased fracture risk, particularly in women
Seek urgent medical attention if you experience any serious symptoms.
Why Do People Choose Competact Tablets?
Competact simplifies diabetes management by combining two medicines into one tablet. People choose it because it reduces tablet burden, strengthens blood sugar control when metformin alone is insufficient, supports improved insulin sensitivity, and targets glucose regulation from two different pathways. For many adults managing type 2 diabetes, a fixed-dose combination tablet makes daily treatment more straightforward and consistent.
How to Order Competact Tablets from Pharmacy Planet
Ordering Competact online is simple and clinically supervised:
- Complete the online consultation and share details about your type 2 diabetes, current treatment, and recent blood sugar readings.
- A qualified UK prescriber checks if Competact is suitable and confirms the correct dosing approach.
- If approved, your Competact tablets are dispensed and delivered discreetly to your chosen address.
Competact tablets offer a combined approach in a single tablet for adults with type 2 diabetes already stabilised on pioglitazone and metformin as separate tablets. Each tablet contains 15mg pioglitazone and 850mg metformin hydrochloride.
This fixed combination simplifies diabetes management. If approved after an online consultation, you can order securely from Pharmacy Planet.
Competact combines pioglitazone (improves insulin sensitivity in muscle, fat, and liver cells) and metformin (reduces glucose production in the liver and improves glucose uptake). This dual mechanism strengthens glucose regulation when metformin alone is no longer enough.
Competact is used when blood sugar remains high despite separate pioglitazone and metformin treatment, when combined therapy is more practical, or when better HbA1c reduction is needed. Response is reviewed after 3 to 6 months.
For adults 18+ only. Usual dose: one 15mg/850mg tablet twice daily (30mg pioglitazone + 1,700mg metformin/day). Take with or just after food, swallowed whole with water.
Not suitable if you have:
- Current or previous heart failure
- Bladder cancer or unexplained blood in urine
- Severe kidney failure (GFR below 30 mL/min)
- Liver impairment or diabetic ketoacidosis
- Acute alcohol intoxication or alcoholism
Like all medicines, Competact may cause side effects.
Common Side Effects:
- Stomach upset, nausea, diarrhoea, weight gain, swelling, headache
Serious Side Effects:
- Heart failure signs, severe allergic reaction, liver problems
- Lactic acidosis (rare), increased fracture risk
Seek urgent medical attention for serious symptoms.
Competact reduces tablet burden, strengthens blood sugar control beyond metformin alone, supports improved insulin sensitivity, and targets glucose regulation from two different pathways — making daily diabetes management more straightforward.
Ordering is simple and clinically supervised:
- Complete the online consultation and share your diabetes history and blood sugar readings.
- A UK prescriber checks suitability and confirms dosing.
- If approved, your tablets are dispensed and delivered discreetly.
Competact can lower blood sugar more effectively than metformin alone when metformin is no longer enough. It combines metformin with pioglitazone to improve glucose regulation from two different angles.
Yes, weight gain can happen with Competact because it contains pioglitazone. The gain may be linked to fluid retention or changes in fat storage, so regular weight checks are important.
A small increased risk of bladder cancer has been reported with long-term pioglitazone use. If you notice blood in your urine or pain when urinating, seek medical advice straight away.
Competact is not suitable for people with heart failure. Pioglitazone can cause fluid retention, which may worsen heart conditions, especially in older adults.
You may be switched to Competact if your blood sugar remains high despite taking the maximum tolerated dose of metformin. It strengthens diabetes management without adding extra tablets.
On its own, Competact rarely causes low blood sugar. The risk increases if it is taken with insulin or certain other anti-diabetic medications.
Yes, kidney function must be checked before starting Competact and monitored regularly. It should not be used if kidney function is severely reduced.
Competact usually begins improving blood sugar within weeks, but HbA1c is typically reviewed after 3 to 6 months to assess how well the treatment is working.
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References:
Review By
HARMINDER ‘HARMY’ KAUR
Last Updated On : Mar 13 2026
BSc(hons) Pharmacy
GPhC Number: 2061107
Authored By
GURDEV SEHMI
Last Reviewed On : Mar 23 2026
BSc Pharm, MRPharmS, Independent Prescriber, Superintendent Pharmacist, Clinical Lead
GPhC Number: 2050925


